摘要
目的探讨尿激酶静脉溶栓联合改良强制性运动疗法在脑梗死治疗中的效果,以期为临床治疗提供参考。方法本研究选取2019年2月—2022年3月在河南省濮阳市人民医院卒中中心就诊的脑梗死患者74例作为研究对象。对照组患者给予常规治疗,观察组患者在对照组治疗基础上给予改良强制性运动疗法干预。治疗结束时(治疗4周时),评估2组患者的治疗效果。比较2组患者治疗前后(治疗4周时)空腹血糖、甘油三酯、总胆固醇水平及Fugl-Meyer量表(FMA)评分。比较2组患者治疗后(治疗4周时)生活质量评定简表(SF-36)评分。结果观察组患者治疗总有效率为97.37%,高于对照组的83.33%,差异有统计学意义(P<0.05)。治疗前,2组患者空腹血糖、甘油三酯、总胆固醇水平比较,差异无统计学意义(P>0.05)。治疗后,2组患者空腹血糖、甘油三酯、总胆固醇水平均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组患者上、下肢FMA评分比较,差异无统计学意义(P>0.05)。治疗后,2组患者上、下肢FMA评分均高于治疗前,且观察组高于对照组,差异均有统计学意义(P<0.05)。观察组患者SF-36中总体健康状况、生理职能、生理功能、情感职能、精神健康及社会功能评分均高于对照组,差异均有统计学意义(P<0.05)。结论尿激酶静脉溶栓联合改良强制性运动疗法能有效改善脑梗死患者的肢体功能,降低血脂、血糖水平,提高患者的总体治疗效果与生活质量,值得临床推广应用。
Objective This study aimed to investigate the effect of intravenous thrombolysis with urokinase combined with modified mandatory exercise therapy in treating cerebral infarction to provide evidence for clinical treatment.Methods Seventy-four patients with cerebral infarction who visited the Stroke Center of Puyang People's Hospital from February 2019 to March 2022 were selected as the study participants.Patients in the control group received conventional treatment,while patients in the observation group received modified mandatory exercise therapy intervention on the basis of the treatment in the control group.At the end of treatment(at 4 weeks of treatment),the treatment outcomes were assessed in both groups.Fasting blood glucose,triglyceride,total cholesterol levels,and Fugl-Meyer Assessment(FMA)scores were compared between the two groups before and after treatment(at 4 weeks of treatment).The 36-Item Short-Form Health Survey(SF-36)scores were compared between the 2 groups after treatment(at 4 weeks of treatment).Results The overall response rate of the observation group was 97.37%,which was significantly higher than that of the control group(83.33%;P<0.05).Before treatment,there was no significant difference in fasting blood glucose,triglyceride,and total cholesterol levels between the two groups(P>0.05).After treatment,fasting blood glucose,triglyceride,and total cholesterol levels in the two groups were lower than those before treatment,and the observation group was lower than the control group,with statistical significance(P<0.05).Before treatment,there was no significant difference in FMA scores of upper and lower limbs between the two groups(P>0.05).After treatment,the FMA scores of upper and lower limbs in the two groups were higher than those before treatment,and the observation group was higher than the control group,with statistical significance(P<0.05).The subscale scores(general health,role-physical,physical functioning,role-emotional,mental health,and social functioning)of SF-36 in the observation
作者
高燕
Gao Yan(Stroke Center,Puyang People's Hospital,Puyang Henan 453100,China)
出处
《保健医学研究与实践》
2023年第4期33-36,41,共5页
Health Medicine Research and Practice
关键词
尿激酶
静脉溶栓
改良强制性运动疗法
脑梗死
Urokinase
Intravenous thrombolysis
Modified mandatory exercise therapy
Cerebral infarction
