摘要
目的开发普通话版宽带噪声数字串测试(broadband digit triplet test,BB-DTT)和低通滤波噪声下数字串测试(low-pass digit triplet test,LP-DTT)材料,验证其检测早期高频听力损失的敏感度和特异性,以期为临床提供一种快速有效的筛查工具。方法录制引导语“数字”及0~9十个数字,将各数字调整至相同的响度(均方根)后进行连接,再与引导语连接后构成测试所用的三位数字串,并通过重复叠加数字串形成测试材料的宽带噪声与低通滤波噪声。招募听力正常者和高频听力损失者各20例,依次进行声导抗、纯音听阈以及BB-DTT和LP-DTT测试,通过每个数字在前置、居中和后置三个位点的结果和需要调整的电平值保证测试材料的同质性,通过测试结果与高频平均听阈的相关性、特征值、敏感度和特异性验证测试材料的有效性。结果①BB-DTT和LP-DTT的SRT阈值与纯音高频平均听阈PTA(3、4、6、8 kHz)之间呈高度相关(Pearson相关系数=0.73、0.71,P<0.01)。②普通话版BB-DTT和LP-DTT测试材料的最佳诊断点分别为-10.5 dB和-15.2 dB。BB-DTT和LP-DTT的受试者工作特性曲线下的面积(AUC)分别为0.97和0.96。③BB-DTT测试材料的敏感度为0.90,特异性为0.95;LP-DTT测试材料的敏感度为0.95,特异性为0.85。结论本研究开发的普通话版BB-DTT、LP-DTT在检测高频听力损失时具有较高的敏感度和特异性,可快速有效地筛查早期高频听力损失。
Objective To develop and apply the Mandarin version of the broadband digit triplet test(BB-DTT)and the low-pass digit triplet test(LP-DTT)to explore their sensitivity and specificity in detecting early high frequency hearing loss,with a view to providing a rapid and effective screening tool for clinical use.Methods The guide word“number”and digit 0~9 were recorded,each number was adjusted to the same RMS loudness level and then connected with the guide word to form a digital triplet test material.The broadband noise and low pass filter noise of the test material were formed by repeated stacking of digital strings.A total of 40 adult subjects were recruited,including 20 normal hearing cases and 20 high-frequency hearing loss cases.Pure tone audiometry,acoustic immittance,BB-DTT and LP-DTT test were performed successively.The homogeneity of the test material was ensured by the results of each digit at the front,center and rear positions.The validity of the test material was analysed by the correlation,eigenvalue,sensitivity and specificity of the test results and the average hearing threshold of high frequency.Results①The SRT threshold of BB-DTT and LP-DTT was highly correlated with the high frequency average hearing threshold of pure tone(Pearson correlation coefficient was 0.73 and 0.71 respectively,P<0.01).②The optimal cut off point of BB-DTT and LP-DTT test were-10.5 dB and-15.2 dB respectively.The area under the subject operating characteristic curve(AUC)of BB-DTT and LP-DTT were 0.97 and 0.96 respectively.③The sensitivity and specificity of BB-DTT were 0.90 and 0.95 respectively.The sensitivity and specificity of LP-DTT test materials were 0.95 and 0.85 respectively.Conclusion The Mandarin version of BB-DTT and LP-DTT developed in this study has high sensitivity and specificity in detecting high frequency hearing loss,and can quickly and effectively screen early hearing loss.
作者
郑宇扬
杨宇
胡旭君
Zheng Yuyang;Yang Yu;Hu Xujun(Zhejiang Chinese Medical University,School of Medical Technology and Information Engineering,Hangzhou,310053,China)
出处
《听力学及言语疾病杂志》
CAS
CSCD
北大核心
2023年第4期318-323,共6页
Journal of Audiology and Speech Pathology
关键词
高频听力损失
听力筛查
数字串
High frequency hearing loss
Hearing screening
Digital triple
