摘要
目的:分析间断高压氧联合氨茶碱治疗重症呼吸衰竭患者的临床疗效。方法:选取2020年4月—2021年2月湖南省衡阳市中心医院重症医学二科收治的重症呼吸衰竭患者80例为观察对象,根据随机数字表法分为对照组与观察组,各40例。对照组给予呼吸机联合氨茶碱治疗,观察组给予间断高压氧联合氨茶碱治疗。比较两组患者血气分析指标、血流动力学指标、临床肺部感染评分(CPIS)、生活质量、肺功能指标。结果:治疗后,观察组血氧饱和度、氧合指数均高于对照组,差异有统计学意义(P<0.001)。治疗后,观察组心率低于对照组,平均动脉压、中心静脉压高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组白细胞计数、气管分泌物、氧合情况、气管吸取物培养、体温、X线胸片、肺部浸润影进展评分低于对照组,差异有统计学意义(P<0.001)。治疗后,观察组生理机能、生理职能、躯体疼痛、情感职能评分高于对照组,差异有统计学意义(P<0.001)。治疗后,观察组一氧化碳弥散量、第1秒用力呼气容积/用力肺活量高于对照组,肺泡内滞留气量水平低于对照组,差异有统计学意义(P<0.001)。结论:间断高压氧联合氨茶碱治疗重症呼吸衰竭患者效果显著,可改善患者血气分析指标、血流动力学指标、肺功能及肺部感染情况,提高生活质量。
Objective:To analyze the clinical efficacy of intermittent hyperbaric oxygen combined with aminophylline in the treatment of patients with severe respiratory failure.Methods:From April 2020 to February 2021,80 patients with severe respiratory failure admitted to the Second Department of Critical Care Medicine,Hengyang Central Hospital,in Hunan Province were selected as observation objects.They were divided into control group and observation group according to the random number table method,with 40 cases in each group.The control group was treated with ventilator combined with aminophylline,and the observation group was treated with intermittent hyperbaric oxygen combined with aminophylline.The blood gas analysis indexes,hemodynamic indexes,Clinical Pulmonary Infection Score(CPIS),quality of life,and lung function indexes in the two groups were compared.Results:After treatment,the oxygen saturation and oxygenation index in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.001).After treatment,the heart rate in the observation group was lower than that in the control group,and the mean arterial pressure and central venous pressure in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the white blood cell count,tracheal secretions,oxygenation,tracheal aspirate culture,body temperature,chest X-ray,and pulmonary infiltrate progress scores in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.001).After treatment,the physiological function,physiological functioning,bodily pain and emotional function scores in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.001).After treatment,the carbon monoxide diffusion capacity and forced expiratory volume in 1 s/forced vital capacity in the observation group were higher than those in the con
作者
刘洋
Liu Yang(Second Department of Critical Care Medicine,Hengyang Central Hospital,Hengyang 421001,Hunan Province,China)
出处
《中国社区医师》
2023年第16期22-24,31,共4页
Chinese Community Doctors
关键词
间断高压氧
氨茶碱
重症呼吸衰竭
Intermittent hyperbaric oxygen
Aminophylline
Severe respiratory failure
