摘要
目的观察解郁化痰饮治疗冠心病经皮冠状动脉介入治疗(PCI)术后焦虑抑郁状态的效果及对患者心理状态的影响。方法本研究纳入冠心病PCI术后焦虑抑郁患者100例,纳入时间2020年9月-2021年6月,采用单纯随机抽样法分为观察组和对照组,各50例,对照组采用常规西药治疗,观察组在对照组基础上联合解郁化痰饮治疗。比较2组临床疗效、中医证候积分、心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)]、中国心血管病人生活质量评定问卷(CQQC)评分、不良反应。结果治疗后,与对照组(84.00%)相比,观察组(96.00%)治疗总有效率较高(P<0.05);2组各项中医证候积分均有所降低(P<0.05);与对照组相比,观察组各项中医证候积分较低(P<0.05);2组SAS、SDS、HAMA、HAMD评分有所降低(P<0.05);与对照组相比,观察组SAS、SDS、HAMA、HAMD评分较低(P<0.05);2组CQQC各项评分均有所提高(P<0.05),与对照组相比,观察组CQQC各项评分较高(P<0.05);2组不良反应发生率无明显差异(P>0.05)。结论常规西药联合解郁化痰饮治疗冠心病PCI术后焦虑抑郁患者有利于提高临床疗效,减轻胸闷(痛)、心悸等症状,改善患者的心理状态和生活质量,安全性较高,具有推广价值。
Objective To observe the effect of Jieyu Huatan Yin in the treatment of anxiety and depression after a percutaneous coronary intervention(PCI)in patients with coronary heart disease(CHD)and its infl uence on their mental statuses.Methods In this study,100 patients with anxiety and depression after PCIs for coronary heart disease were included from September 2020 to June 2021.They were randomly divided into an observation group and a control group,with 50 patients in each group.The control group was treated with conventional western medicine,while the observation group was treated with Jieyu Huatan Yin on the basis of that.The clinical efficacy,TCM syndrome scores,mental status scores[Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS),Hamilton Anxiety Scale(HAMA),Hamilton Depression Scale(HAMD)],Chinese Cardiovascular Patient Quality of Life Questionnaire(CQQC)scores and adverse reactions of the two groups were compared.Results After treatment,the total eff ective rate of the observation group(96.00%)was higher than that of the control group(84.00%)(P<0.05).After treatment,the scores of TCM symptoms in both groups were decreased(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the scores of SAS,SDS,HAMA and HAMD in the two groups were decreased(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).After treatment,the scores of CQQC in both groups were improved(P<0.05),and the CQQC scores of the observation group were higher than those of the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion In the treatment of patients with anxiety and depression after PCIs for coronary heart disease,the combination of conventional western medicine and Jieyu Huatan Yin is conducive to improving their clinical effi cacy,relieving the chest distress(pain),palpitation and other symptoms,and improving the psychological status
作者
王海霞
秦晓敏
吴珊珊
赵自冰
牛燕运
WANG Haixia;QIN Xiaomin;WU Shanshan;ZHAO Zibing;NIU Yanyun(Department of Cardiology,Handan Hospital of Traditional Chinese Medicine,Handan 056001,China;Department of Pharmacy,Handan Hospital of Traditional Chinese Medicine,Handan 056001,China;Second Department of Encephalopathy,Handan Hospital of Traditional Chinese Medicine,Handan 056001,China)
出处
《吉林中医药》
2023年第6期674-678,共5页
Jilin Journal of Chinese Medicine
基金
河北省中医药管理局科研计划项目(2021467)。
关键词
冠心病
经皮冠状动脉介入治疗
焦虑抑郁
解郁化痰饮
心理状态
coronary heart disease
percutaneous coronary intervention
anxiety and depression
Jieyu Huatan Yin
mental status
