摘要
目的探讨肺癌患者术后住院期间发生恶心呕吐的危险因素。方法根据是否发生术后恶心呕吐(PONV)将103例接受手术治疗的肺癌患者分为PONV组(n=30,发生PONV)和对照组(n=73,未发生PONV)。收集患者临床资料,包括基本信息、血液检查结果、辅助检查结果、病史、手术资料、麻醉资料及术后24 h病历记录。采用多因素Logistic回归模型分析肺癌患者术后住院期间发生恶心呕吐的危险因素。结果术后住院期间,30例(29.1%)患者发生恶心呕吐,均发生于术后24 h内。单因素分析结果显示,PONV组中年龄﹤65岁、女性、体重指数﹤18.5 kg/m^(2)、C反应蛋白﹥5 mg/L、手术时间≥3 h、有慢性胃病史、临床分期Ⅲ~Ⅳ期的患者比例均高于对照组,差异均有统计学意义(P﹤0.05)。多因素Logistic回归模型分析结果显示,年龄﹤65岁、女性、手术时间≥3 h以及慢性胃病史均是肺癌患者术后住院期间发生恶心呕吐的危险因素(P﹤0.05)。结论年龄﹤65岁、女性、手术时间≥3 h以及慢性胃病史均是肺癌患者术后住院期间发生恶心呕吐的危险因素。
Objective To analyze the risk factors for nausea and vomiting during postoperative hospitalization of lung cancer patients.Method According to occurrence of postoperative nausea and vomiting(PONV),103 lung cancer patients treated surgically were divided into PONV group(n=30,occurred PONV)and control group(n=73,not occurred PONV).The clinical data including basic information,results of hematology and supportive examination,medical history,surgical data,anesthesia information and medical record 24 hours after surgery were collected.The risk factors for nausea and vomiting during postoperative hospitalization of lung cancer patients were analyzed by multivariate Logistic regression model.Result A total of 30 patients(29.1%)developed nausea and vomiting during postoperative hospitalization,all of which occurred within 24 hours after surgery.The univariate analysis showed the proportion of patients with age<65 years,female,body mass index<18.5 kg/m^(2),C-reactive protein>5 mg/L,operation time≥3 h,history of chronic gastric disease and clinical stage III-IV in the PONV group were higher than those in the control group,the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that age<65 years,female,operation time≥3 h,and history of chronic gastric disease were risk factors of nausea and vomiting during postoperative hospitalization in patients with lung cancer(P<0.05).Conclusion Age<65 years,female,operation time≥3 h,and history of chronic gastric disease are risk factors of nausea and vomiting during postoperative hospitalization in patients with lung cancer.
作者
白彦慧
岳佩如
郑秀青
BAI Yanhui;YUE Peiru;ZHENG Xiuqing(Department of General Medicine,the First Affiliated Hospital of He’nan University of Chinese Medicine,Zhengzhou 450000,He’nan,China;Department of Pediatrics,the First Affiliated Hospital of He’nan University of Chinese Medicine,Zhengzhou 450000,He’nan,China)
出处
《癌症进展》
2023年第8期870-873,共4页
Oncology Progress
关键词
肺癌
恶心呕吐
危险因素
手术
lung cancer
nausea and vomiting
risk factor
surgery
