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氟哌利多与托烷司琼预防直肠脱垂注射消痔灵术后恶心呕吐的效果观察

The Efficacy of Droperidol plus Tropisetron in Preventing Vomiting and Nausea Following Xiaozhiling Injection for Rectal Prolapse
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摘要 目的:观察氟哌利多与托烷司琼预防直肠脱垂注射消痔灵术导致的恶心呕吐的效果。方法:将162例直肠脱垂患者分为氟哌利多组(F组)79例和托烷司琼组(T组)83例。患者入室后,常规监测。开放静脉,静脉注射阿托品0.5mg,实施骶管麻醉,成功后静脉注射芬太尼0.1mg,开放随机分配信封,取出二次包装的药品,静脉入壶。随后术者暴露脱垂的直肠,根据直肠脱垂面积大小注射消痔灵混合液80~100mL。观察术后当天与术后第1天患者恶心呕吐(PONV)分级状况。结果:术后当天F组患者PONV发生率低于T组(P<0.05),术后第1天2组患者PONV发生率比较差异无统计学意义(P>0.05)。结论:F组优于T组,氟哌利多用于预防术后恶心呕吐效果满意。 Objective To observe the efficacy of droperidol plus tropisetron in preventing nausea&vomiting following Xiaozhiling injection for rectal prolapse(RP).Methods Divided 162 RP patients into droperidol group(also,F group,79 cases)and tropisetron group(also,T group,83 cases),then,routinely monitored all patients after they entered room,opened their venous,intravenously injected them with atropine 0.5mg,performed sacral anesthesia on patients,after success,intravenously injected them with fentanyl 0.1mg;opened random distribution envelope,took secondary packed drugs,into venous bottle;afterwards patients’exposed their prolapsed rectum,according to the area of prolapsed rectum,injected Xiaozhiling mixture(80-100mL)into it;observed patients’situation of PONV grading on nausea&vomiting on the day of operation,and on 1st day after operation.Results On the day of operation in PONV incidence F group was lower than T group(P<0.05);on 1st day after operation in PONV incidence there was no statistical difference between the two groups(P>0.05).Conclusion F group is superior to T group;Droperidol for preventing postoperative nausea&vomiting has satisfactory efficacy.
作者 赵艳艳 赵新生 韩宝 ZHAO Yan-yan;ZHAO Xin-sheng;HAN Bao(Mayinglong Changqing Hospital for Coloproctological Diseases,Beijing 100195)
出处 《中国肛肠病杂志》 2022年第4期53-54,共2页 Chinese Journal of Coloproctology
基金 北京中医药科技发展资金项目(课题编号:JJ2016-06)。
关键词 直肠脱垂 消痔灵 恶心呕吐 氟哌利多 托烷司琼 Rectal prolapse Xiaozhiling injection Nausea&vomiting Droperidol Tropisetron
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