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药物超敏反应综合征并发血管免疫母细胞性T细胞淋巴瘤一例

Drug hypersensitivity syndrome was complicated by vascular immunoblasts of T-cell lymphoma in one case
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摘要 药物超敏反应综合征(DIHS)又称伴嗜酸性粒细胞增多和系统症状的药物反应(DRESS),是一种少见且可危及生命的药物不良反应。血管免疫母细胞性T细胞淋巴瘤(AITL)是一种非霍奇金淋巴瘤,在目前世界卫生组织的淋巴瘤分类中被归类为外周性T细胞非霍奇金淋巴瘤-淋巴结型,临床十分罕见。DIHS和AITL都有发热、皮疹、淋巴结肿大等表现,在临床上互为鉴别诊断,在临床诊断过程中也容易漏诊。本文报告成都中医药大学附属医院重症医学科收入的1例DIHS并发AITL典型病例。 Drug induced hypersensitivity syndrome(DIHS),also known as the drug reaction with eosinophilia and systemic symptoms(DRESS),is a rare and life-threatening adverse drug reaction.Angioimmunoblastic T-cell lymphoma(AITL)is a non-Hodgkin lymphoma,classified as a peripheral T-cell non-Hodgkin lymphoma-lymph node type in the current World Health Organization lymphoma classification.It is clinically rare.DIHS and AITL have symptoms such as fever,rash and swollen lymph nodes,which are clinically differential diagnosis and easy to miss diagnosis during clinical diagnosis.This paper reports a typical case of DIHS complicated with AITL in the Department of Critical Care Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine.
作者 黎立 孙玮婷 郭留学 高培阳 LI Li;SUN Wei-ting;GUO Liu-Xue(Clinical Medicine School of Chengdu University of Traditional Chinese Medicine,Chengdu 610000,China;不详)
出处 《医师在线》 2023年第6期47-50,共4页 Journal of Doctors Online
关键词 药物超敏反应综合征 血管免疫母细胞性T细胞淋巴瘤 发热 皮疹 淋巴结肿 Drug hypersensitivity syndrome Angioimmunoblastic T-cell lymphoma Fever Rash Lymphadenoma
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