摘要
目的探讨退热药物对乙酰氨基酚和布洛芬引起儿童急性荨麻疹的不良反应的发生及有效治疗方法。方法临床药师全程开展药学服务,分析1例3岁患儿使用对乙酰氨基酚和布洛芬退热治疗后均出现急性荨麻疹的临床案例,并进行相关讨论。结果患儿出现急性荨麻疹后,口服地氯雷他定干混悬剂抗过敏、地塞米松抗炎抗过敏和抗病毒药物治疗,最终患儿症状好转。结论乙酰氨基酚和布洛芬同致急性荨麻疹的不良反应报道较为少见但仍存在,患儿用药后需密切观察,出现急性荨麻疹时可予抗过敏治疗。临床药师进行药物相关性不良反应的评分和分析,旨在为临床合理用药提供参考。
Objective To explore the effective treatment to urticaria induced by acetaminophen and ibuprofen and pharmaceutical care.Methods The clinical case of one three-year-old child of acute urticaria induced by acetaminophen and ibuprofen were reviewed retrospectively.Results Desloratadine dry suspension and dexamethasone were administered to this child with acute urticaria and a good prognosis was observed.Conclusion Acute urticaria induced by acetaminophen and ibuprofen was rare but still present in clinical practice.The children should be monitoring as well as anti-allergic treatment when treated with acetaminophen and ibuprofen.Besides,the analysis of drug-related adverse reactions by clinical pharmacist may provide the reference for clinical practice.
作者
叶桂花
李华敏
YE Guihua;LI Huamin(Shanghai Ninth People′s Hospital Hainan Branch/Hainan Western Central Hospital,Danzhou 571700,China)
出处
《药学研究》
CAS
2023年第5期358-360,共3页
Journal of Pharmaceutical Research
