摘要
目的:探讨婴幼儿呼吸道沙眼衣原体(CT)感染的流行特征及趋势,为制订高效的防治对策提供依据。方法:回顾性选取2020年9月-2022年12月赣州市妇幼保健院收治的324例呼吸道感染婴幼儿,所有患儿给予CT聚合酶链反应(PCR)-荧光探针法检测,并进行流行病学特征分析。结果:324例呼吸道感染婴幼儿中,CT阳性例数16例,总体感染率为4.94%;1~3个月、4个月~1岁、>1岁患儿CT感染率分别为7.19%、4.95%和1.19%,且随着年龄的增长,CT感染率呈下降趋势(χ^(2)=3.925,P=0.048);男、女患儿CT感染占比分别为4.72%、5.08%,比例为1∶1.67;CT感染主要集中在冬季,感染率为11.11%,占CT感染总体的50.00%(8/16)。CT感染婴幼儿家属成员所属职业中,农林渔牧、商业服务、在家务业/待业、餐饮食品和医疗服务分别位列前5,感染率为7.26%,占CT感染总体的81.25%(13/16),占呼吸道感染婴幼儿群体的4.01%(13/324)。CT阳性组直系亲属带病、家族聚集发病情况与CT阴性组相比,差异均有统计学意义(P<0.05)。结论:婴幼儿CT感染在年龄、季节和家庭成员所属职业上的分布呈现不同的流行特点,患儿家属应加强呼吸道感染的预防,降低感染风险。
Objective:To explore the epidemic characteristics and trends of respiratory tract chlamydia trachomatis(CT)infection and provide the basis for formulating effective prevention and control countermeasures.Method:A total of 324 infants with respiratory tract infection admitted to Ganzhou Women and Children's Health Care Hospital from September 2020 to December 2022 were retrospectively selected,and all the infants were detected by CT polymerase chain reaction(PCR)-fluorescence probe method,and the epidemiological characteristics were analyzed.Result:Among 324 infants with respiratory tract infection,16 cases were CT positive,and the overall infection rate was 4.94%.The infection rates of CT in children aged 1-3 months,4 months-1 year,and>1 year respectively was 7.19%,4.95%and 1.19%,and with the increase of age,the CT infection rate showed a downward trend(χ^(2)=3.925,P=0.048).The proportion of CT infection in male and female children respectively was 4.72%and 5.08%,and the ratio was 1∶1.67.CT infection is mainly concentrated in winter,with an infection rate of 11.11%,accounting for 50.00%(8/16)of the total CT infection.Among the occupations of family members of infants with CT infection,agriculture,forestry,fishery and animal husbandry,business services,housework/unemployment,catering food and medical staff ranked the top five,with an infection rate of 7.26%,accounting for 81.25%(13/16)of the total CT infection and 4.01%(13/324)of the infants population with respiratory tract infection.There were significant differences in the incidence of disease and family cluster in the CT positive group compared with the CT negative group(P<0.05).Conclusion:The distribution of CT infection in infants shows different epidemic characteristics in age,season and occupation of family members.Family members of children should strengthen the prevention of respiratory tract infection to reduce the risk of infection.
作者
李源
刘建平
LIYuan;LIU Jianping(Ganzhou Women and Children's Health Care Hospital,Jiangxi Province,Ganzhou 341000,China;不详)
出处
《中国医学创新》
CAS
2023年第14期59-62,共4页
Medical Innovation of China
基金
江西省卫生健康委科技计划项目(202212330)。
关键词
婴幼儿
呼吸道感染
沙眼衣原体
流行病学特点
Infants
Respiratory tract infection
Chlamydia trachomatis
Epidemiological characteristics
