摘要
中国是乙肝大国,慢性乙型肝炎孕妇的病理、疾病进展与肠道微生态健康密切相关。“肠-肝轴”假说认为肠道菌群是肠道和肝脏相互作用的重要中介。研究表明益生菌具有抗乙肝病毒活性,能够预防妊娠并发症的发生。本综述就乙肝对肠道菌群、妊娠并发症的影响,以及益生菌干预功效进行综述,为通过益生菌调节肠道微生态改善乙肝孕妇健康提供科学参考。
Hepatitis B is an endemic in China,and the pathology and disease progression of chronic hepatitis B in pregnant women are highly related to the health of gut microbiome.The“gut-liver axis”hypothesis proposes that gut microbiota is an important mediator of gut-liver interactions.Studies have shown that probiotics have anti-hepatitis B virus activity and can prevent pregnancy complications.This article reviewed the influences of hepatitis B on intestinal flora and pregnancy complications,as well as the efficacy of probiotics intervention.It provides a scientific reference for improving the health of pregnant women with hepatitis B by regulating intestinal microbiome through probiotics.
作者
魏鑫越
王起山
赵军英
刘彦品
陈历俊
WEI Xinyue;WANG Qishan;ZHAO Junying;LIU Yanpin;CHEN Lijun(School of Bioengineering,Dalian Polytechnic University,Dalian 116034;National Engineering Center of Dairy for Maternal and Child Health,Beijing Engineering Research Center of Dairy,Beijing Technical Innovation Center of Human Milk Research,Beijing Sanyuan Foods Co.,Ltd.,Beijing 100163)
出处
《中国食品添加剂》
CAS
北大核心
2023年第5期24-31,共8页
China Food Additives
基金
国家自然科学基金项目(32072191)
大兴区重大科技成果转化项目(2020006)
家畜产业技术体系北京市创新团队项目
北京市科技专项(Z201100002620005)。
关键词
益生菌
益生元
肠道微生物
乙肝病毒
孕妇
妊娠并发症
probiotics
prebiotics
gut microbes
hepatitis B virus
pregnant women
pregnancy complications
