摘要
目的探讨24 h动态脉压(24 h ambulatory pulse pressure,24 hAPP)及24 h动态脉压指数(24 h ambulatory pulse pressure index,24 hAPPI)在进展性脑梗死患者中的变化分析及与预后的相关性。方法便利选择2019年6月—2021年4月山东省菏泽市立医院收治的进展性脑梗死患者61例作为研究对象,发病后3个月以门诊复诊随访,按照NIHSS评分评估患者预后,根据评估结果分为预后良好组(37例)与预后不良组(24例)。采用无创性动态血压监测仪完成24 hAPP、24 hAPPI水平测定,完成预后单因素与多因素Logistic回归分析;分析24 hAPP、24 hAPPI与患者预后的关系。结果61例进展性脑梗死患者中24例患者预后不佳,占39.34%。多因素Logistic结果表明:年龄(OR=7.982)、高血压(OR=6.791)、接诊时NIHSS评分(OR=6.632)、24 hAPP(OR=4.313)、24 hAPPI(OR=6.323)是进展性脑梗死患者预后的危险因素(P<0.05)。Pearson相关性分析结果表明:进展性脑梗死患者预后不良与24 hAPP、24 hAPPI水平均呈正相关性(P<0.05)。结论24 hAPP、24 hAPPI水平在进展性脑梗死患者中呈高表达,且与患者预后存在强相关性,能为临床诊疗提供参考依据。
Objective To investigate the changes of 24 h ambulatory pulse pressure(24 hAPP)and 24 h ambulatory pulse pressure index(24 hAPPI)in patients with progressive cerebral infarction and their correlation with prognosis.Methods 61 patients with progressive cerebral infarction admitted to Heze Municipal Hospital in Shandong Province from June 2019 to April 2021 were conveniently selected as the research subjects,and they were followed up in an outpatient clinic 3 months after the onset.The prognosis of the patients was evaluated according to the NIHSS score,and they were divided into a good prognosis group(37 cases)and a poor prognosis group(24 cases)according to the evaluation results.The level of 24 hAPP and 24 hAPPI were measured by non-invasive ambulatory blood pressure monitor,and the single factor and multivariate Logistic regression analysis of prognosis were completed;the relation⁃ship between 24 hAPP,24 hAPPI and the prognosis of patients was analyzed.Results Among the 61 patients with progressive cerebral infarction,24 patients had poor prognosis,accounting for 39.34%.Multivariate Logistic results showed:age(OR=7.982),hypertension(OR=6.791),NIHSS score at the time of consultation(OR=6.632),24 hAPP(OR=4.313),24 hAPPI(OR=6.323)were risk factors for the prognosis of patients with progressive cerebral infarction(P<0.05).The results of Pearson correlation analysis showed that the poor prognosis of patients with progressive cere⁃bral infarction was positively correlated with the levels of 24 hAPP and 24 hAPPI(P<0.05).Conclusion The levels of 24 hAPP and 24 hAPPI are highly expressed in patients with progressive cerebral infarction,and there is a strong cor⁃relation with the prognosis of patients,which can provide a reference for clinical diagnosis and treatment.
作者
刘印叶
刘伟丽
王文文
李素霞
李新果
LIU Yinye;LIU Weili;WANG Wenwen;LI Suxia;LI Xinguo(Department of Neurology,Heze Municipal Hospital,Heze,Shandong Province,274000 China;Department of Neurology,People's Hospital of Juancheng County,Heze,Shandong Province,274000 China;Shandong Heze Medical College,Heze,Shandong Province,274000 China)
出处
《中外医疗》
2023年第1期10-13,共4页
China & Foreign Medical Treatment
关键词
24
h动态脉压
24
h动态脉压指数
进展性脑梗死
预后
相关性
24-hour ambulatory pulse pressure
24-hour ambulatory pulse pressure index
Progressive cerebral infarction
Prognosis
Correlation
