摘要
目的探索合并高血压的急性Stanford A型主动脉夹层(AAAD)患者的临床特征与影响短期预后的因素。方法回顾性连续收集2012年1月至2021年5月在西京医院就诊的AAAD患者,分析合并高血压AAAD患者的临床特征,并将单因素分析中P<0.1的因素纳入多因素Logistic回归,探索与AAAD预后相关的独立危险因素。结果共纳入AAAD患者2033例,高血压组1354例(67.3%),非高血压组679例(32.7%)。院内全因死亡234例,病死率11.5%,组间比较无统计学差异(χ^(2)=2.238,P=0.135)。多因素Logistic回归分析结果表明体重、D-二聚体是AAAD患者院内死亡的独立危险因素(P<0.05),外科手术及腔内介入治疗是AAAD患者院内死亡的保护因素。结论合并高血压AAAD患者存在年龄更大、体重更重等临床特点,但合并高血压不是其院内死亡的独立危险因素。
Objective To explore the clinical characteristics and short-term prognostic factors in patients with acute Stanford A aortic dissection(AAAD)complicated with hypertension.Methods The clinical characteristics of AAAD patients with hypertension treated in Xijing Hospital from January 2012 to May 2021 were analyzed retrospectively.Factors with P<0.1 in univariate analysis were included into multivariate logistic regression to explore independent risk factors related to prognosis of AAAD.Results A total of 2033 patients with AAAD were included,1354(67.3%)in the hypertension group and 679(32.7%)in the non-hypertension group.There were 234 cases of all-cause deaths in hospital,with a mortality rate of 11.5%.There was no statistical difference between groups(χ^(2)=2.238,P=0.135).Multivariate logistic regression analysis showed that body weight and D-dimer were independent risk factors for in-hospital death of AAAD patients(P<0.05),and surgery and endovascular intervention were protective factors for in-hospital death of AAAD patients.Conclusion Patients with AAAD combined with hypertension have the clinical characteristics of older age and heavier weight,but hypertension is not an independent risk factor for hospital death.
作者
丁伟
段维勋
王伟光
薛超
俞波
任恺
金振晓
杨晨
王东旭
刘金成
Ding Wei;Duan Weixun;Wang Weiguang;Xue Chao;Yu Bo;Ren Kai;Jin Zhenxiao;Yang Chen;Wang Dongxu;Liu Jincheng(Department of Cardiovascular Surgery,First Affiliated Hospital of Air Force Medical University,Shaanxi Xi'an 710032,China)
出处
《中国体外循环杂志》
2023年第2期92-97,共6页
Chinese Journal of Extracorporeal Circulation
基金
国家自然科学基金面上项目(82070503,82070264)
陕西省重点研发计划(2022ZDLSF01-09,2022ZDLSF02-01)。
关键词
急性主动脉夹层
高血压
预后
Acate aortic dissection
Hypertension
Prognosis
