摘要
目的探讨血清胆红素(TBil)、糖化血红蛋白(HbAlc)及血脂(TG、TC、LDL-C、HDL-C)联合检验对诊断2型糖尿病合并冠心病的价值。方法选择上海交通大学医学院苏州九龙医院2020年1月—2022年5月收治的50例2型糖尿病合并冠心病患者为观察组,另取同期收治的50例2型糖尿病患者为对照组,检测并比较两组TBil、HbAlc及血脂水平,另分析联合检验的诊断价值。结果观察组TBil、HDL-C低于对照组;HbAlc、TG、TC、LDL-C均高于对照组,差异有统计学意义(t=7.192、5.141、9.018、16.130、3.474、6.456,P<0.05)。联合诊断准确率90.00%、特异度96.00%,较TBil、HbAlc、血脂单独检验准确率更高,差异有统计学意义(χ^(2)=11.000、23.000、12.000、12.000、28.000、16.000,P<0.05);灵敏度84.00%,与单独检验差异无统计学意义(χ^(2)=0.000、3.200、1.333,P>0.05)。结论2型糖尿病合并冠心病患者TBil、HbAlc及血脂指标均存在明显异常,联合检测能提高诊断准确率。
Objective To investigate the value of serum bilirubin(TBil),glycosylated hemoglobin(HbAlc)and blood lipid(TG,TC,LDL-C,HDL-C)combined test in the diagnosis of type 2 diabetes mellitus complicated with coronary heart disease.Methods 50 patients with type 2 diabetes mellitus complicated with coronary heart disease admitted to Suzhou Jiulong Hospital,Shanghai Jiaotong University School of Medicine from January 2020 to May 2022 were se⁃lected as the observation group,and another 50 patients with type 2 diabetes admitted during the same period were se⁃lected as the control group.The levels of TBil,HbAlc and blood lipid in the two groups were detected and compared,and the diagnostic value of combined test was analyzed.Results TBil and HDL-C in the observation group were lower than those in the control group,HbAlc,TG,TC,LDL-C were significantly higher than those in the control group,the difference was statistically significant(t=7.192,5.141,9.018,16.130,3.474,6.456,P<0.05).The accuracy rate of combined diagnosis was 90.00%,and the specificity was 96.00%,which was higher than that of TBil,HbAlc and blood lipid test alone,the difference was statistically significant(χ^(2)=11.000,23.000,12.000,12.000,28.000,16.000,P<0.05).The sensitivity was 84.00%,and there was no statistically significant difference between the two tests(χ^(2)=0.000,3.200,1.333,P>0.05).Conclusion TBil,HbAlc and blood lipid indexes were significantly abnormal in pa⁃tients with type 2 diabetes mellitus and coronary heart disease.Combined detection could improve the diagnostic accu⁃racy.
作者
张凯
杨凯
胡振华
ZHANG Kai;YANG Kai;HU Zhenhua(Department of Clinical Laboratory,Suzhou Jiulong Hospital,School of Medicine,Shanghai Jiaotong University,Suzhou,Jiangsu Province,215000 China)
出处
《系统医学》
2023年第1期98-100,105,共4页
Systems Medicine
关键词
2型糖尿病
冠心病
血清胆红素
糖化血红蛋白
血脂
Type 2 diabetes mellitus
Coronary heart disease
Serum bilirubin
Glycosylated hemoglobin
Blood fat
