摘要
目的:探讨胎盘商及胎盘血管指数在妊娠11-13^(+6)周对FGR的诊断价值。方法:前瞻性连续收集2021年10月-2022年10月在石河子大学第一附属医院行产前颈项透明层厚度检查的单胎妊娠孕妇195名作为研究对象,并采集孕11-13^(+6)周胎盘容积及胎盘血管指数,并对所有孕妇进行随访直至出生后,根据随访结果分为FGR组(n=16例)和正常组(n=179例)。利用虚拟组织计算机辅助分析软件(VOCAL)进行脱机分析,获得胎盘容积及胎盘血管指数。结果:FGR组胎盘商、胎盘血管化指数、血管化-血流指数均小于正常组,差异有统计学意义(P<0.05);胎盘商分别联合胎盘血管指数VI、FI、VFI诊断胎儿生长受限的ROC曲线下面积分别为0.7800、0.6713、0.7874,胎盘商联合血管指数VFI指标诊断FRG的效能最高(AUC=0.7874)。结论:胎盘商及胎盘血管指数可以为早孕期诊断FGR提供量化指标,更有助于临床制定有效的干预措施,降低其不良妊娠结局发生,值得推广应用。
Objective:To investigate the diagnostic value of placental quotient and placental vascular index in patients with FGR at 11-13^(+6) weeks of gestation.Methods:A total of 195 pregnant women with single pregnancy who underwent prenatal Nuchaltranslucency(NT)test at the First Affiliated Hospital of Shihezi University Medical College from October 2021 to October 2022 were prospectively and continuously collected.Placental volume and placental vascular index were collected at 11-13^(+6) weeks of gestation.All pregnant women were followed up until birth and divided into FGR group(n=16 cases)and normal group(n=179 cases)according to the follow-up results.Placental volume and placental vascular index were obtained by using virtual tissue computer aided analysis software(VOCAL).Results:The placental quotient,placental vasculization index and vasculization blood flow index in FGR group were lower than those in normal group,and the difference was statistically significant(P<0.05).The areas under ROC curve of placental quotient combined with placental vascular index VI,FI and VFI in diagnosing fetal growth restriction were 0.7800,0.6713 and 0.7874,respectively.The efficacy of placental quotient combined with vascularowth rr index VFI in diagnosing FRG was the highest(AUC=0.7874).Conclusions:Placental merchant and placental vascular index can provide quantitative indicators for the diagnosis of FGR in early pregnancy,which is more helpful for clinical development of effective intervention measures to reduce the occurrence of adverse pregnancy outcomes, and is worthy of popularization and application.
作者
唐琳
安睿
陈玲
TANG Lin;AN Rui;CHEN Ling(Shihezi University School of Medicine,Xinjiang Shihezi,832002;Ultrasound Room of obstetrics and gynecology,the First Affiliated Hospital of Shihezi University,Xinjiang Shihezi,832008)
出处
《农垦医学》
2023年第1期1-4,9,共5页
Journal of Nongken Medicine
基金
石河子大学第一附属医院重点基金项目(DZ201902)。
关键词
胎儿生长受限
胎盘商
血管指数
三维能量多普勒超声
Fetal gestriction
Placenta merchant
Vascular index
Three-dimensional energy Doppler ultrasound
