摘要
目的探索肺磨玻璃结节(GGN)的多层螺旋CT特征表现及预后。方法选取的58例GGN患者均在2020年1—8月驻马店市中心医院收集,并进行CT检查,分析良恶性结节CT影像特征,比较良恶性结节CT值和血管密度。根据预后情况分为两组,即预后良好组(n=48,生存者)和预后不佳组(n=10,死亡或病情进展者),经受试者工作特征(ROC)曲线分析预后预测效能。结果细支气管肺泡癌(BAC)患者结节≥1.0 cm,边缘毛刺征、毛糙、光整,密度为Ⅱ~Ⅲ型;腺癌患者结节≥1.0 cm,呈分叶征,不规则为主,密度为Ⅱ~Ⅲ型;炎症患者结节以≤0.9 cm、斑块状为主,密度为Ⅰ型;不典型腺瘤样增生(AAH)患者边缘光整,密度为Ⅰ型。恶性结节者CT值、血管密度高于良性结节者(P<0.05)。经ROC曲线分析,CT值、血管密度诊断GGN恶性结节的曲线下面积(AUC)分别为0.900、0.884。预后不佳者CT值、血管密度高于预后良好者(P<0.05),经ROC曲线分析,CT值、血管密度预测GGN恶性结节预后的AUC分别为0.950、0.900。结论CT在GGN良恶性结节分辨以及预后预测中均具有一定价值。
Objective To explore the features and prognosis of pulmonary ground glass nodules(GGN)with multi-slice spiral CT.Methods The selected 58 GGN patients were collected from January to August 2020 from Zhumadian Central Hospital,and all underwent CT examination.The CT imaging characteristics of benign and malignant nodules were analyzed,and the CT values and blood vessel density of benign and malignant nodules were compared.According to the prognosis,they were divided into two groups,namely,a good prognosis group(n=48,survivors)and a poor prognosis group(n=10,those who died or disease progression).The receiver operating characteristic(ROC)curve was used to analyze the prognosis prediction performance.Results The nodules in bronchioloalveolar carcinoma(BAC)patients were≥1.0 cm,with spiculated edges,roughness and smoothness,and the density was typeⅡ-Ⅲ.In patients with adenocarcinoma,the nodules were≥1.0 cm,mainly lobulated and irregular,and the density was typeⅡ-Ⅲ.The nodules of patients with inflammation were mainly≤0.9 cm and patchy,and the density was typeⅠ.In patients with atypical adenomatous hyperplasia(AAH),the edge was smooth,and the density was typeⅠ.The CT value and blood vessel density of malignant nodules were higher than those of benign nodules(P<0.05).According to the ROC curve,the area under the curve(AUC)of CT value and vascular density in diagnosing malignant nodules of GGN were 0.900 and 0.884,respectively.The CT value and vascular density of patients with poor prognosis were higher than those of patients with good prognosis(P<0.05).According to ROC curve,the AUC of CT value and vascular density in predicting the prognosis of malignant nodules of GGN were 0.950 and 0.900,respectively.Conclusion CT has a certain value in distinguishing benign and malignant nodules and predicting prognosis in GGN.
作者
王赢
代向党
张宏凯
WANG Ying;DAI Xiangdang;ZHANG Hongkai(Department of Radiology,Zhumadian Central Hospital,Zhumadian 463000,China;Department of Radiology,Henan Cancer Hospital,Zhengzhou 450000,China)
出处
《河南医学研究》
CAS
2023年第7期1249-1252,共4页
Henan Medical Research
关键词
肺磨玻璃结节
多层螺旋CT
特征表现
预后
pulmonary ground glass nodules
multi-slice spiral CT
characteristic manifestations
prognosis
