摘要
综述基于尿酸转运蛋白调控机制探讨中药改善高尿酸血症的实验研究进展。研究发现,中药单体及其有效成分、复方可通过影响尿酸重吸收转运蛋白、尿酸分泌转运蛋白表达,进而发挥降低血尿酸水平的作用。
The research progress of traditional Chinese medicine in improving hyperuricemia by regulating uric acid transporter was reviewed.Studies had found that the traditional Chinese medicine monomers,active components and compounds could reduce the level of serum uric acid by affecting the expression of uric acid reabsorption transporters and uric acid secretion transporters.
作者
辛家东
高建东
XIN Jiadong;GAO Jiandong(Department of Nephrology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Institute of Traditional Chinese Nephropathy,Shanghai University of Traditional Chinese Medicine,Key Laboratory of Liver and Kidney Diseases(Ministry of Education),Shanghai 201203,China)
出处
《上海中医药杂志》
CSCD
2023年第2期14-20,共7页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(81874437,81904126)
上海市科委科技计划项目(20Y21901800)。
关键词
高尿酸血症
痛风
中药
尿酸转运蛋白
作用机制
研究进展
hyperuricemia
gout
traditional Chinese herbal medicine
uric acid transporter
mechanism of action
research progress