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基于人体成分分析的个体化体质量管理对抗精神病药物所致肥胖患者的疗效观察

Observation on the efficacy of individualized weight management based on body composition analysis in obese patients caused by antipsychotic drugs
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摘要 目的 探讨基于人体成分分析的个体化体质量管理对抗精神病药物所致肥胖患者的疗效。方法 选择2021年01月至2021年12月浙江省衢州市第三医院收治的36例抗精神病药物所致肥胖患者作为研究对象,随机分为研究组和对照组,每组各18例。对照组予常规健康指导,研究组在对照组基础上增加基于人体成分分析的个体化体质量管理措施,比较两组患者体质量管理前后体质量、体质量指数(body mass index,BMI)、人体成分分析相关指标的变化。结果 管理后,两组患者的体质量、BMI明显下降,研究组患者的体质量、BMI明显低于对照组(P<0.05)。两组患者的基础代谢(basal metabolism,BM)、肌肉量(muscle contraction,MC)、总体脂(total body fat,TBF)、非脂肪组织指数(fat free mass index,FFMI)、总能量消耗(total energy expenditure,TEE)等与管理前比较,差异均有统计学意义(P<0.05),但总体水(total body water,TBW)管理前后差异不明显(P>0.05);且除TBW外,研究组患者管理后的BM、MC、TBF、FFMI、TEE较对照组明显改善(P<0.05)。结论 基于人体成分分析的个体化体质量管理措施可有效降低抗精神病药物所致肥胖患者的BMI,提高基础代谢和机体TEE,增加机体MC,降低TBF。 Objective To explore the efficacy of individualized weight management based on body composition analysis in obese patients caused by antipsychotic drugs.Methods A total of 36 patients with obesity caused by antipsychotic drugs in the Third Hospital of Quzhou City in Zhejiang Province from January 2021 to September 2021 were collected as the research objects,and were randomly divided into study group and control group,with 18 cases in each group.The control group was given regular health guidance,and the study group added individualized weight management measures based on body composition analysis on the basis of the control group,and the changes in weight,BMI,and body composition analysis related indicators before and after weight management were compared.Results After management,the body mass and BMI of patients in the two groups decreased significantly,and the body mass and BMI of patients in the study group were significantly lower than those in the control group(P<0.05).The basic metabolism(BM),muscle contract(MC),total body fat(TBF),fat free mass index(FFMI),total energy expenditure(TEE) of the two groups were significantly different from those before management,the difference was statistically significant(P<0.05).However,there was no significant difference in total body water(TBW) indicators before and after management(P>0.05).In addition to TBW,BM,MC,TBF,FFMI and TEE of patients in the study group were significantly improved compared with those in the control group after management(P<0.05).Conclusion Individualized weight management measures based on body composition analysis can effectively reduce the body mass index of obese patients caused by antipsychotic drugs,increase basal metabolism and total body energy consumption,increase body muscle content,and reduce TBF.
作者 王雪莲 余颖 WANG Xuelian;YU Ying(Department of Gerontology,the Third Hospital of Quzhou City in Zhejiang Province,Quzhou 324000,Zhejiang,China)
出处 《中国现代医生》 2023年第9期57-60,共4页 China Modern Doctor
关键词 人体成分分析 个体化体质量管理 抗精神病药物 肥胖 Body composition analysis Individualized weight management Antipsychotic drugs Obesity
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