摘要
创伤性急性弥漫性脑肿胀(PADBS)是一种较为常见的重型创伤性脑损伤(TBI),其短时间内可以导致颅内压急剧增高,病情急且危重,致残率与致死率高。目前,PADBS的发生机制仍不明确,所涉及的学说包括急性脑血管扩张、脑水肿和颅内静脉循环障碍等。且PADBS尚缺少统一的诊断标准,主要依靠CT等影像学检查,其去骨瓣减压手术的指征与时机仍存在争议。为此,笔者就PADBS的发生机制、诊断与治疗等方面的研究进展进行综述,为PADBS的救治提供一些新思路。
Posttraumatic acute diffuse brain swelling(PADBS)is a relatively common severe traumatic brain injury(TBI).Since it can lead to acute intracranial hypertension in a short time,the illness can be acute and critical,with a high disability and fatality rate.The pathogenesis of PADBS is still unclear,with the current theory consisting of acute cerebral vasodilation,cerebral edema and intracranial venous circulation disorder.For PADBS,there is still a lack of unified diagnostic criteria,and the indications and timing of decompression craniectomy remain controversial.The authors review the research progress in the pathogenesis,diagnosis and treatment of PADBS,hoping to provide some new ideas for its treatment.
作者
傅世龙
鲜亮
王守森
Fu Shilong;Xian Liang;Wang Shousen(Department of Neurosurgery,First Hospital of Putian City,Putian 351100,China;Department of Neurosurgery,Fuzong Clinical Medical College of Fujian Medical University(900th Hospital of Joint Logistics Support Force),Fuzhou 350025,China)
出处
《中华创伤杂志》
CAS
CSCD
北大核心
2023年第3期283-288,共6页
Chinese Journal of Trauma
关键词
颅脑损伤
颅内高压
脑水肿
弥漫性脑肿胀
Craniocerebral trauma
Intracranial hypertension
Brain edema
Diffuse brain swelling
