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鞘内输注吗啡治疗重度癌痛引起头晕及头痛不良反应1例 被引量:2

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摘要 患者女,38岁,以“肺癌术后3年,胸背部疼痛7个月”于哈尔滨医科大学附属肿瘤医院疼痛科接受鞘内药物输注系统(IDDS)植入术。患者术后持续输注吗啡,每日剂量为4.5~4.8 mg,出现头痛、头晕、恶心、耳鸣症状;爆发痛发作给予追加量后,上述症状加重,平卧后症状减轻。患者入院后连续3次脑脊液常规均未见异常,血常规未见异常,无畏寒、发热,排除颅内感染可能。予以甘露醇治疗后,患者头痛、头晕、恶心及耳鸣症状缓解,因此考虑为输注吗啡引起的颅内压增高。停用鞘内吗啡后,改用舒芬太尼持续镇痛治疗,患者不良反应消失,疼痛控制稳定后出院。
作者 滕蕾 邹慧超
出处 《中华医学杂志》 CAS CSCD 北大核心 2023年第9期700-701,共2页 National Medical Journal of China
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