摘要
目的:比较超声引导下生理盐水灌肠与X线引导下空气灌肠复位治疗肠套叠患儿的效果。方法:选取2019年9月至2020年10月该院收治的102例肠套叠患儿进行前瞻性研究,采用简单化随机法将其分为对照组和研究组各51例。对照组采用X线引导下空气灌肠复位疗法,研究组采用超声引导下生理盐水灌肠复位疗法。比较两组复位成功率、复位时间、住院时间、治疗前后胃肠激素[胃泌素(GAS)、胃动素(MTL)]水平、炎性因子[C反应蛋白(CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]水平及并发症发生率。结果:研究组复位成功率(94.12%)与对照组(84.31%)比较,差异无统计学意义(P>0.05);研究组复位时间、住院时间均短于对照组,差异有统计学意义(P<0.05);治疗后,两组GAS、MTL、CRP、TNF-α、IL-6水平均较治疗前明显下降,且研究组低于对照组,差异有统计学意义(P<0.05);研究组并发症发生率为5.88%(3/51),低于对照组的19.61%(10/51),差异有统计学意义(P<0.05)。结论:超声引导下生理盐水灌肠复位治疗肠套叠患儿能够缩短复位时间和住院时间,减轻炎症反应,改善胃肠功能,降低并发症发生率,优于X线引导下空气灌肠复位的效果。
Objective:To compare effects of ultrasound guided saline enema and X-ray guided air enema in reduction treatment of intussusception in children.Methods:A prospective study was conducted on 102 children with intussusception admitted to the hospital from September 2019 to October 2020.They were divided into control group and study group by using the simplified randomized method,51 cases in each.The control group was treated with X-ray guided air enema while the study group was treated with ultrasound guided saline enema.The reduction success rate,the reduction time,the hospitalization time,the levels of gastrointestinal hormones[gastrin(GAS),motilin(MTL)],the inflammatory factor levels[serum C-reactive protein(CRP),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)],and the incidence of complications were compared between the two groups.Results:The reduction success rate in the study group(94.12%)was not significantly different from that in the control group(84.31%)(P>0.05).The reduction time and the hospitalization time in the study group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the GAS,MTL,CRP,TNF-α and IL-6 levels in both groups decreased compared to those before the treatment,those in the study group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the study group was 5.88%(3/51),lower than 19.61%(10/51)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Ultrasound guided saline enema can shorten the reduction time and the hospitalization time,alleviate the inflammatory reactions,improve the gastrointestinal function,and reduce the incidence of complications in the children with intussusception,which is superior to X-ray guided air enema reduction.
作者
蒋明珠
JIANG Mingzhu(Pediatric Surgery Department of Zhumadian Central Hospital,Zhumadian 463000 Henan,China)
出处
《中国民康医学》
2023年第6期132-135,共4页
Medical Journal of Chinese People’s Health
关键词
肠套叠
超声引导
患儿
生理盐水灌肠
空气灌肠
胃肠激素
炎性因子
Intussusception
Ultrasound guidance
Children
Saline enema
Air enema
Gastrointestinal hormone
Inflammatory factor