摘要
目的探讨超声引导下水压灌肠对急性肠套叠(acute intussusception,AI)患儿应激反应及胃肠激素的影响。方法选择2018年3月至2019年8月我院收治的AI患儿148例,采用随机数字表法分为超声组76例和X射线组72例。超声组采用超声引导下水压灌肠治疗,对照组采用X射线引导下空气灌肠治疗,比较两组患儿治疗效果、应激反应、胃肠激素及并发症。结果超声组AI患儿复位成功率98.68%高于X射线组91.67%,复发率和并发症低于X射线组(P<0.05),复位时间、大便隐血恢复时间、住院时间短于X射线组(P<0.01);血清白细胞介素-6(IL-6)、C-反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)含量低于X射线组(P<0.01);血清胃动素(MTL)、胃泌素(GAS)、神经降压素(NT)含量低于X射线组(P<0.01)。结论超声引导下水压灌肠有助于缓解AI患儿炎症应激反应,降低胃肠激素水平,提高治疗效果,减少并发症的发生。
Objective To investigate the stress response of water pressure enema under the guidance of ultrasound for children with acute intussusception(AI).Methods One hundred and forty-eight children with AI in our hospitals from March 2018 to August 2019 were divided into ultrasonic group(n=76)and X-ray group(n=72).The ultrasound group given ultrasound-guided water enema while the control group given X-ray guided air enema.The therapy effect,stress reaction,gastrointestinal hormones and complications were compared between the two groups.Results The reduction successful rate in the ultrasound group was 98.68%which was higher than that in the X-ray group(91.67%).The recurrence rate and complications in the ultrasound group was lower than that in the X-ray group(P<0.05).The reduction time,fecal occult blood recovery time,and hospital stay time in the ultrasound group were shorter than that in the X-ray group(P<0.01).The levels of serum IL-6,CRP,TNF-α,MTL,GAS and NT in the ultrasound group were lower than those in the X-ray group(P<0.01).Conclusion The water pressure enema under the guidance of ultrasound helps to alleviate the inflammatory stress response,reduce the gastrointestinal hormone levels,improve the therapy effect and reduce the complications.
作者
张龙
杨军
余世万
孙凯
向远超
魏艳青
黄兰露
ZHANG Long;YANG Jun;YU Shi-wan;SUN Kai;WEI Yan-qing;HUANG Lan-lu(Department of Pediatric Surgery,Nanyang Second People's Hospital,Nanyang 473000,China)
出处
《实用医院临床杂志》
2021年第1期27-30,共4页
Practical Journal of Clinical Medicine
基金
河南省医学科技攻关项目(编号:LHGJ20191468)。
关键词
急性肠套叠
超声
水压灌肠
应激反应
胃肠激素
Acute intussusception
Ultrasound
Water pressure enema
Stress response
Gastrointestinal hormone
