摘要
目的:分析血清B型脑钠肽(BNP)、降钙素原(PCT)、超敏C反应蛋白(hs-CRP)水平与重症肺炎合并心力衰竭患者心功能分级的相关性。方法:选取2019年1月至2021年2月该院收治的100例重症肺炎患者为研究对象,依据是否合并心力衰竭将其分为单纯组47例和合并组53例,另选取同期本院50名健康体检者为对照组。比较三组血清BNP、PCT、hs-CRP水平,依据美国心脏病协会(NYHA)心功能分级标准,比较合并组不同心功能分级患者血清BNP、PCT、hs-CRP水平,采用Pearson相关性分析血清BNP、PCT、hs-CRP水平与重症肺炎合并心力衰竭患者心功能分级的相关性。结果:合并组血清BNP、PCT、hs-CRP水平均高于单纯组和对照组,且单纯组高于对照组,差异有统计学意义(P<0.05);合并组心功能分级Ⅳ级患者血清BNP、PCT、hs-CRP水平均高于Ⅱ级和Ⅲ级,且Ⅲ级高于Ⅱ级,差异有统计学意义(P<0.05);Pearson相关性分析结果显示,血清BNP、PCT、hs-CRP水平与重症肺炎合并心力衰竭患者心功能分级呈正相关(r>0,P<0.05)。结论:重症肺炎合并心力衰竭患者血清BNP、PCT、hs-CRP水平升高,且与患者心功能分级呈正相关。
Objective:To analyze correlations among serum B-type brain natriuretic peptide(BNP),procalcitonin(PCT),high-sensitivity C-reactive protein(hs-CRP)levels and cardiac function classification in patients with severe pneumonia complicated with heart failure.Methods:100 patients with severe pneumonia admitted to the hospital from January 2019 to February 2021 were selected as the research objects.According to whether the patients had heart failure,they were divided into simple group(47 cases)and combined group(53 cases).Another 50 healthy subjects were selected as the control group.The levels of serum BNP,PCT and hs-CRP were compared among the three groups.According to the American Heart Association(NYHA)cardiac function classification standard,the serum BNP,PCT and hs-CRP levels of the patients with different cardiac function classifications in the combined group were compared.Pearson correlation analysis was used to analyze the correlations among the serum BNP,PCT,hs-CRP levels and the cardiac function classification in the patients with severe pneumonia complicated with heart failure.Results:The levels of serum BNP,PCT and hs-CRP in the combined group were higher than those in the control group and the simple group,and the simple group was higher than the control group,and the differences were statistically significant(P<0.05).The levels of serum BNP,PCT and hs-CRP in the patients with cardiac function classification Ⅳ in the combined group were higher than those in the patients with classification Ⅱ and classification Ⅲ,those in the patients with classification Ⅲ were higher than those in the patients with classification Ⅱ,and the differences were statistically significant(P<0.05).Pearson correlation analysis showed that serum BNP,PCT and hs-CRP levels were positively correlated with the cardiac function classification in the patients with severe pneumonia complicated with heart failure(r>0,P<0.05).Conclusions:The levels of the serum BNP,PCT and hs-CRP in the patients with severe pneumonia complicated wi
作者
彭莉丽
裴素莉
宋立
PENG Lili;PEI Suli;SONG Li(Department of Respiratory Medicine of Nanjing Red Cross Hospital,Nanjing 210000 Jiangsu,China)
出处
《中国民康医学》
2023年第6期123-125,共3页
Medical Journal of Chinese People’s Health
基金
南京市医学科技发展课题,课题名称:慢性阻塞性肺疾病健康状况评估及急性加重预测的研究(YKK13224)。
关键词
重症肺炎
心力衰竭
血清B型脑钠肽
降钙素原
超敏C反应蛋白
相关性
Severe pneumonia
Heart failure
Serum B-type brain natriuretic peptide
Procalcitonin
Hypersensitive C-reactive protein
Correlation
