摘要
目的探究不同浓度罗哌卡因在全髋关节置换术患者全身麻醉中的应用效果。方法90例进行全身麻醉全髋关节置换术治疗的患者作为研究对象,根据患者全身麻醉中使用罗哌卡因浓度的不同分成A组(0.15%)、B组(0.25%)、C组(0.50%),每组30例。比较三组患者手术过程中不同时点的血流动力学指标(心率、平均动脉压),麻醉效果(感觉阻滞起效时间、平面固定时间、运动阻滞起效时间),麻醉苏醒指标(呼吸恢复时间、睁眼时间、拔管时间),术后麻醉不良反应发生情况。结果麻醉前,三组患者的心率、平均动脉压比较,差异无统计学意义(P>0.05);麻醉后5、10、15 min,三组患者的心率、平均动脉压均低于本组麻醉前,但A组患者的心率、平均动脉压均高于B组及C组,B组患者的心率、平均动脉压均高于C组,差异具有统计学意义(P<0.05)。A组患者的心率、平均动脉压下降幅度小,心率、平均动脉压较为平稳。三组患者的感觉阻滞起效时间、平面固定时间、运动阻滞起效时间两两比较,差异均无统计学意义(P>0.05)。A组患者的呼吸恢复时间(10.27±1.34)min、睁眼时间(10.28±1.20)min、拔管时间(10.38±1.45)min均短于B组的(12.58±2.01)、(12.79±1.82)、(12.71±2.05)min及C组的(14.34±2.35)、(14.57±2.00)、(14.39±2.41)min,B组患者的呼吸恢复时间、睁眼时间、拔管时间均短于C组,差异具有统计学意义(P<0.05)。A组患者的不良反应发生率3.33%低于B组的20.00%及C组的20.00%,差异具有统计学意义(P<0.05);B组与C组患者的不良反应发生率比较,差异无统计学意义(P>0.05)。结论在全髋关节置换术患者全身麻醉中,应用0.15%、0.25%、0.50%罗哌卡因均可以获得理想的麻醉效果,但是相比之下0.15%罗哌卡因在获得相当麻醉效果的同时,可以获得较好的麻醉苏醒效果,麻醉苏醒不良反应少,是更为理想的罗哌卡因药物浓度。
Objective To investigate the application effect of different concentrations of ropivacaine in general anesthesia for patients undergoing total hip arthroplasty.Methods A total of 90 patients undergoing general anesthesia for total hip arthroplasty were studied,and the patients were divided into group A(0.15%),group B(0.25%),and group C(0.50%)according to different concentrations of ropivacaine used in general anesthesia,with 30 patients in each group.Comparison was made on hemodynamic indexes(heart rate,mean arterial pressure)at different time points during surgery,anesthetic effects(onset time of sensory block,plane fixation time,onset time of motor block),anesthesia recovery indexes(respiratory recovery time,eye opening time,extubation time),and the occurrence of postoperative anesthetic adverse reactions among the three groups.Results Before anesthesia,the heart rate and mean arterial pressure in the three groups were compared,and the difference was not statistically significant(P>0.05).At 5,10 and 15 min after anesthesia,the heart rate and mean arterial pressure in all three groups were lower than those before anesthesia in this group;but the heart rate and mean arterial pressure in group A were higher than those in group B and group C;the heart rate and mean arterial pressure in group B were higher than those in group C;the differences were statistically significant(P<0.05).In group A,the heart rate and mean arterial pressure decreased slightly,and the heart rate and mean arterial pressure were relatively stable.There was no statistically significant difference in the onset time of sensory block,plane fixation time and onset time of motor block among the three groups(P>0.05).Group A had respiratory recovery time of(10.27±1.34)min,eye opening time of(10.28±1.20)min,and extubation time of(10.38±1.45)min,which were shorter than those of(12.58±2.01),(12.79±1.82),and(12.71±2.05)min in group B,and(14.34±2.35),(14.57±2.00),and(14.39±2.41)min in group C;the respiratory recovery time,eye opening time and ext
作者
朱国红
石玉琴
ZHU Guo-hong;SHI Yu-qin(General Global China Railway Pizhou Hospital,Xuzhou 221300,China)
出处
《中国实用医药》
2023年第7期23-26,共4页
China Practical Medicine
关键词
全髋关节置换术
全身麻醉
罗哌卡因
麻醉效果
麻醉苏醒
麻醉不良反应
Total hip arthroplasty
General anesthesia
Ropivacaine
Anesthesia effect
Recovery from anesthesia
Adverse anesthetic reaction
