摘要
条件性基因编辑动物和病毒载体作为有效的科研工具已经被广泛应用于生物学和医学等研究领域。近年来它们在针灸实验研究中也得到了应用,成为从神经系统到特定分子层面更好地揭示针灸作用机制的有效手段。为了增进对条件性基因编辑动物和病毒载体的了解,本文在分析这两种工具特征和优势的基础上,进一步结合二者在针灸实验研究方面的具体应用,探讨它们今后在针灸实验研究中可能发挥的作用及应用前景。
Conditional gene editing animals and viral vectors have been widely applied in the research fields of biology and medicine.Recently,they are also used as the effective approaches to reveal the underlying mechanism of acupuncture from the nervous system to the specific molecules.In order to further understand the application of conditional gene editing animals and viral vectors,in this article,we analyze their characteristics,advantages and recent development in the field of acupuncture research and discuss their potential roles and prospect in the future.
作者
刘一寒
崔晶晶
李宇清
徐东升
陈淑萍
白万柱
LIU Yi-han;CUI Jing-jing;LI Yu-qing;XU Dong-sheng;CHEN Shu-ping;BAI Wan-zhu(Institute of Acupuncture and bustion,China Academy of Chinese Medical Sciences,Beijing 100700,China)
出处
《针刺研究》
CAS
CSCD
北大核心
2023年第3期299-304,共6页
Acupuncture Research
基金
中国中医科学院科技创新工程资助项目(No.CI2021A03407)
国家自然科学基金资助项目(No.81774211、81774432、81801561、82004492)。
关键词
针灸
条件性基因编辑
病毒载体
光遗传
化学遗传
Acupuncture
Conditional gene editing
Viral vectors
Optogenetics
Chemogenetics
