摘要
目的 探讨定经汤加味联合针灸治疗肾虚肝郁型更年期综合征抑郁症状的临床效果。方法 选取2021年3月至2022年3月常德市第一中医医院医治的更年期综合征抑郁症患者70例作为研究对象,根据随机数表法将其分成常规组和试验组,每组各35例,前者给予定经汤加味治疗,后者给予定经汤加味联合针灸治疗。比较两组治疗前后抑郁自评量表评分、血清性激素水平、中医证候积分、神经内分泌指标、匹兹堡睡眠质量指数(PSQI)评分等指标变化情况。结果 两组患者治疗前汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评分比较,差异均无统计学意义(P> 0.05)。两组患者治疗后HAMD、HAMA均低于本组治疗前,差异有统计学意义(P <0.05);试验组治疗后HAMD、HAMA评分均低于常规组,差异有统计学意义(P <0.05)。两组患者治疗前血清促卵泡成熟激素(FSH)、促黄体生成激素(LH)、雌二醇(E2)比较,差异均无统计学意义(P> 0.05)。两组患者治疗后FSH、LH水平均低于本组治疗前,E2水平均高于本组治疗前,差异有统计学意义(P <0.05);试验组治疗后FSH、LH水平均低于常规组,E2水平均高于常规组,差异有统计学意义(P <0.05)。两组患者治疗前中医证候积分、PSQI评分比较,差异均无统计学意义(P> 0.05)。两组患者治疗后中医证候积分、PSQI评分均低于本组治疗前,差异有统计学意义(P <0.05);试验组治疗后中医证候积分、PSQI评分均低于常规组,差异有统计学意义(P <0.05)。两组患者治疗前中性粒细胞(NE)、多巴胺(DA)浓度比较,差异均无统计学意义(P> 0.05)。两组患者治疗后NE、DA浓度均高于本组治疗前,差异有统计学意义(P <0.05);试验组治疗后NE、DA浓度均高于常规组,差异有统计学意义(P <0.05)。结论 对肾虚肝郁型更年期综合征抑郁症患者给予定经汤加味联合针灸治疗效果显著,其能够改善患者心理状态,有效调节患者神
Objective To study the clinical effect of Dingjing Decoction plus acupuncture and moxibustion on depression of climacteric syndrome of kidney deficiency and liver depression.Methods From March 2021 to March 2022,70 patients with climacteric syndrome depression who were treated in Changde First Hospital of Traditional Chinese Medicine were selected as the research objects,and they were divided into a routine group and a test group according to the method of digital random table,with 35 cases in each group.The former was treated with modified Dingjing Decoction,and the latter was treated with modified Dingjing Decoction combined with acupuncture and moxibustion.The changes of the scores of the self-rating depression scale,serum sex hormone levels,TCM syndrome scores,neuroendocrine indicators,Pittsburgh sleep quality index(PSQI)and other indicators were compared before and after treatment.Results There was no significant difference in the scores of Hamilton depression scale(HAMD)and Hamilton anxiety scale(HAMA)between the two groups before treatment(P>0.05).After treatment,the HAMD and HAMA of patients in the two groups were lower than those before treatment,the difference was statistically significant(P<0.05).After treatment,the scores of HAMD and HAMA in the test group were lower than those in the conventional group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in serum follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)between the two groups before treatment(P>0.05).After treatment,the levels of FSH and LH in the two groups were lower than those before treatment,and the levels of E2 were higher than those before treatment,the difference was statistically significant(P<0.05).After treatment,the levels of FSH and LH in the test group were lower than those in the conventional group,and the levels of E2 were higher than those in the conventional group,the difference was statistically significant(P<0.05).There was no significant differ
作者
楼炎灵
李振龙
LOU Yaning;LI Zhenong(Department of Internal Medicine of TCM,No.1 Traditional Chinese Medicine Hospital in Changde,Hunan,Changde415000,China;Department of Cardiology,No.1 Traditional Chinese Medicine Hospital in Changde,Hunan,Changde 415000,China)
出处
《中国医药科学》
2023年第5期20-24,32,共6页
China Medicine And Pharmacy
关键词
定经汤加味
针灸
肾虚肝郁
更年期综合征
抑郁症
影响
Modified Dingjing Decoction
Acupuncture and moxibustion
Menopausal syndrome with kidney deficiency and liver depression
Depression
Effect
