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输尿管软镜与微通道经皮肾镜碎石术治疗2~3 cm肾结石的疗效及安全性比较 被引量:8

Comparison of the efficacy and safety of flexible ureteroscope and micro channel percutaneous nephrolithotomy in the treatment of 2-3 cm renal calculi
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摘要 目的 探讨输尿管软镜(FURL)与微通道经皮肾镜碎石术(MPCNL)治疗长径2~3 cm肾结石的疗效及安全性.方法 选择本院2017年1月至2020年1月期间收治的98例肾结石患者,按照不同治疗方式分为对照组和研究组,每组各49例,其中对照组采用MPCNL治疗,研究组采用FURL治疗.观察并比较两组患者的各项手术情况(包括手术时间、术中出血量、术后下床活动时间、住院时间)、结石清除率、疼痛与舒适度评分及手术前后的生存质量情况(包括生理机能、躯体疼痛、健康状况等).结果 研究组的手术时间、术中出血量、术后下床活动时间、住院时间均优于对照组,差异均有统计学意义(均P<0.001).研究组术后3 d的结石清除率高于对照组,差异有统计学意义(P<0.05),但两组术后1周及1个月的结石清除率比较,差异均无统计学意义(均P>0.05).研究组术后5、48 h的疼痛评分低于对照组,舒适度评分高于对照组,差异均有统计学意义(均P<0.05).治疗前两组患者的生存质量情况比较,差异无统计学意义(P>0.05);出院时研究组的生存质量情况高于对照组,差异有统计学意义(P<0.05).结论 使用FURL、MPCNL治疗结石长径2~3 cm的肾结石均有较好的效果,但FURL的手术时间较短并能够缩短患者住院时间,且术后生存质量情况较高,患者疼痛舒适度较好,具有良好的临床优势. Objective To investigate the efficacy and safety of flexible ureteroscope(FURL)and minimally invasive percutaneous nephrolithotomy(MPCNL)in the treatment of 2-3 cm renal calculi.Methods From January 2017 to January 2020,98 patients with renal calculi in our hospital were selected and divided into two groups according to different treatment methods,with 49 cases in each group.The control group was treated with MPCNL,and the study group was treated with FURL.The operation conditions,stone clearance rate,pain and comfort score and quality of life of the two groups were observed.Results The operation time,intraoperative blood loss,postoperative ambulation time,and hospitalization time in the study group were better than those in the control group,and the differences were statistically significant(all P<0.001).The stone clearance rate of the study group was higher than that of the control group at 3 days after operation,and the difference was statistically significant(P<0.05),but there was no statistically significant difference in the stone clearance rate between the two groups at 1 week and 1 month after operation(all P>0.05).The pain scores of the study group at 5 h and 48 h after surgery were lower than those of the control group,and the comfort scores were higher than those of the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the quality of life between the two groups before treatment(P>0.05).The quality of life of the study group was higher than that of the control group at discharge,the differences were statistically significant(P<0.05).Conclusions FURL and MPCNL are good for 2-3 cm renal calculi,but FURL can shorten the operation time,shorten the hospitalization time,improve the postoperative quality of life,and improve the pain comfort of patients.
作者 蔡奕川 黄耀林 洪英洽 Cai Yichuan;Huang Yaolin;Hong Yingqia(Department of Urology,Chaozhou Central Hospital,Chaozhou 521000,China)
出处 《国际泌尿系统杂志》 2023年第2期200-203,共4页 International Journal of Urology and Nephrology
关键词 肾结石 输尿管镜检查 肾造口术 经皮 碎石术 Kidney Calculi Ureteroscopy Nephrostomy,Percutaneous Lithotripsy
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