摘要
产前糖皮质激素(ACS)的应用可有效降低早产儿病率与死亡率,是改善早产儿预后的重要产前干预措施。由于不同孕周胎儿发育和成熟情况不同,对ACS的反应存在差异,因此应基于孕周使用ACS。文章将结合国内外文献及指南就不同孕周使用ACS的药物学基础、临床研究证据、争议、指南推荐几个方面进行阐述,以期为临床实践提供参考。
The application of antenatal corticosteroid(ACS)can effectively reduce the morbidity and mortality of premature infants,and it is an important prenatal intervention to improve the prognosis of premature infants.The use of ACS should be based on the gestational age due to different fetal development and different responses to ACS.In this paper,the pharmacologic basis,clinical research evidence,controversy and guideline recommendation of ACS at different gestational age will be reviewed based on domestic and foreign literature and guidelines,hoping to provide reference for clinical practice.
作者
周术卫
王岚
漆洪波
ZHOU Shu-wei;WANG Lan;QI Hong-bo(Department of Obstetrics and Gynecology,Chongqing Health Center for Women and Children,Women and Children's Hospital of Chongqing Medical University,Chongqing 401147,China)
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2023年第2期160-165,共6页
Chinese Journal of Practical Gynecology and Obstetrics
基金
重庆市科卫联合医学科研项目(2023GGXM005)。
关键词
产前糖皮质激素
孕周
早产
antenatal corticosteroid
gestational age
premature birth
