摘要
目的了解本地区胃息肉的发病趋势及发病特点,比较不同类型胃息肉的发病影响因素,为胃息肉的防治提供理论依据。方法回顾性分析2015年9月—2020年8月青岛大学附属医院收治的3204例胃息肉病人的临床及内镜病理资料,于2019—2020年随机选取有或无胃息肉的210例病人进行焦虑量表现况问卷调查。结果5年间在青岛大学附属医院消化内科住院并行胃镜检查的病人15844例,检出胃息肉3204例,检出率为20.22%,其中男性1025例,女性2179例。5年间胃息肉检出率逐年升高,胃底腺息肉所占比例呈逐年上升趋势,腺瘤性息肉、增生性息肉、炎性息肉所占比例呈逐年下降趋势,胃底部息肉所占比例呈逐年上升趋势,胃窦部息肉所占比例呈逐年下降趋势(χ^(2)=52.181、68.824,P<0.01)。胃息肉的病理类型与病人的性别、年龄,胃息肉的大小、数目、发生部位,病人幽门螺杆菌(Hp)感染情况、胃黏膜萎缩及肠上皮化生的发生和严重程度有关。焦虑状态在胃息肉与非胃息肉病人中差异明显,是胃息肉发病的独立危险因素(OR=5.233,P<0.01)。结论胃息肉是上消化道的常见疾病,检出率逐年升高。青岛地区人群最常见的胃息肉类型是胃底腺息肉和增生性息肉,过去5年间增生性息肉占比明显下降,胃底腺息肉占比明显上升,提示对于质子泵抑制剂的长期应用以及Hp感染根除治疗方案的选择应更加谨慎。该病治疗需结合胃息肉病理类型及临床发病特点制定个体化诊疗方案。
Objective To investigate the incidence trend and features of gastric polyps in Qingdao,China and the influencing factors for different types of gastric polyps,and to provide a theoretical basis for the prevention and treatment of gastric polyps.Methods A retrospective analysis was performed for the clinical data and endoscopic pathological data of 3204 patients with gastric polyps who were admitted to The Affiliated Hospital of Qingdao University from September 2015 to August 2020,and a questionnaire survey on anxiety was performed among 210 patients with or without gastric polyps in 2019-2020.Results In the past five years,15844 patients were hospitalized and underwent gastroscopy in Department of Gastroenterology,The Affiliated Hospital of Qingdao University,among whom 3204 were found to have gastric polyps,resulting in a detection rate of 20.22%,and there were 1025 male patients and 2179 female patients.The detection rate of gastric polyps showed an increasing trend in the past five years;the proportion of fundic gland polyps tended to increase year by year,and the proportion of adenomatous polyps,hyperplastic polyps,and inflammatory polyps tended to decrease year by year;the proportion of fundic polyps tended to increase year by year,and the proportion of antral polyps tended to decrease year by year(χ2=52.181,68.824;P<0.05).The pathological type of gastric polyps was associated with sex,age,the size,number,and location of gastric polyps,Helicobacter pylori(Hp)infection,and the occurrence and severity of gastric mucosal atrophy and intestinal metaplasia.The anxiety state was significantly different between the patients with gastric polyps and those without gastric polyps,and was an independent risk factor for the onset of gastric polyps(OR=5.233,P<0.01).Conclusion Gastric polyp is a common disease of the upper gastrointestinal system,and its detection rate is increasing year by year.Fundic gland polyps and hyperplastic polyps are the most common types of gastric polyps in Qingdao,and there is a significant r
作者
张硕
綦鹏
宋科秀
刘俊衡
ZHANG Shuo;QI Peng;SONG Kexiu;LIU Junheng(Department of Gastroenterology,The Affiliated Hospital of Qingdao University,Qingdao 266500,China)
出处
《青岛大学学报（医学版）》
CAS
2023年第1期79-86,共8页
Journal of Qingdao University(Medical Sciences)
基金
海南省医药卫生科研项目(1902320242A2-001)
山东省自然科学基金项目(ZR2021QH171)。
关键词
胃息肉
危险因素
胃镜检查
疾病特征
幽门螺杆菌
stomach polyps
risk factors
gastroscopy
disease attributes
Helicobacter pylori
