摘要
目的21世纪以来我国高原病研究取得了快速发展,本文旨在探索国内高原病领域的研究热点和科学前沿,为该领域的后续研究提供参考。方法以CNKI数据库为检索对象,选取发表于2000年1月—2021年7月的3797篇文献,借助CiteSpace科学计量工具进行计量学分析并绘制知识图谱。结果2000—2021年高原病研究文献数量总体呈上升趋势,研究热点集中在以“高原肺水肿、高原脑水肿及高原红细胞增多症”为主要病种的病因、病理、临床防治及其高海拔因素的探索性研究。近3年研究前沿主要集中在以“氧化应激”和“炎症反应”为代表的病理机制、高原病磁共振成像及高原医学3个方面。结论近20年来国内高原病研究集中在急慢性高原病的临床诊治、病因病理方向,与高原病相关的生物化学、分子遗传学及环境职业健康等内容较少,未来应加强高原病的分子生物化学、遗传学及环境健康等方向的研究,推进高原病的系统性、整体性研究。
Objective Since the 21st century,the research on altitude sickness has achieved rapid development in China.The purpose of this paper is to explore the research hotspots and scientific frontiers in the field of altitude sickness in China,and to provide reference for the follow-up research in this field.Methods Taking CNKI database as the search object,3797 articles published from January 2000 to July 2021 were selected.CiteSpace scientific measurement tool was used to carrying out the metrological analysis and knowledge mapping.Results The number of literature on plateau sickness was generally on the rise from2000 to 2021.The research focuses on the etiology,pathology and clinical prevention and treatment of"high altitude pulmonary edema,high altitude brain edema and high altitude polycythemia",as well as the exploratory research on high altitude factors.The pathological mechanism represented by"oxidative stress"and"inflammatory response",magnetic resonance imaging of altitude sickness and altitude medicine are the research frontiers in the past three years.Conclusions The study of altitude sickness focus on the directions of clinical diagnosis and treatment,etiology and pathology of acute or chronic plateau sickness in the past 20years.There are few literature on biochemistry,molecular genetics and environmental occupational health related to altitude sickness.In the future,it is necessary to strengthen the researches on molecular biochemistry,genetics and environmental health to promote the systematic and holistic study of altitude sickness.
作者
宗咏花
欧霞
张燕飞
许明珠
张雪芹
莫歌
ZONG Yong-hua;OU Xia;ZHANG Yan-fei;XU Ming-zhu;ZHANG Xue-qin;MO Ge(Teaching-research Office of Modern Medicine,Tibet University of Tibetan Medicine,Lhasa Tibet,850000,China;Department of Basic Medicine,Sichuan Vocational College of Nursing,Mianyang Sichuan,610100,China)
出处
《职业与健康》
CAS
2023年第1期107-114,共8页
Occupation and Health
基金
西藏自治区藏医药区域协同创新项目(2019XTCX006)。
关键词
高原病
知识图谱
研究热点
高原医学
Altitude sickness
Knowledge mapping
Research focus
High altitude medicine
