摘要
目的:探讨全腹腔镜胃癌根治术(totally laparoscopic gastrectomy,TLG)在胃癌患者中的近期疗效和安全性评价。方法:回顾性分析2019年1月—2020年12月在中国科学技术大学附属第一医院住院治疗的296例胃癌患者,按是否进行腹腔内消化道重建分为全腹腔镜组(TLG组,n=140,行TLG治疗)和腹腔镜辅助组[腹腔镜辅助胃癌根治术(laparoscopy assisted gastrectomy,LAG)组,n=156,行LAG治疗];对两组术前、术中及术后的临床资料进行比较。结果:TLG组的手术时间、术后住院时间、切口长度均显著短于LAG组,通气时间、进食流质时间早于LAG组,术中出血量少于LAG组,术后1 d、术后3 d的疼痛评分及术后1 d白细胞计数低于LAG组,差异均有统计学意义(P<0.05)。TLG组和LAG组的肿瘤直径、近远端切缘距离、肿瘤分化程度、淋巴结清扫数和TNM分期比较,差异均无统计学意义(P>0.05)。结论:与LAG相比,TLG创伤更小,术后恢复更快,术后住院时间更短,治疗效果更好,且不增加术后并发症风险。
Objective:To evaluate the short-term outcomes and safety of total laparoscopic gastrectomy(TLG)in patients with gastric cancer.Method:A retrospective analysis was made of 296 patients with gastric cancer who were hospitalized in the First Affiliated Hospital of the University of Science and Technology of China from January 2019 to December 2020.They were divided into total laparoscopic gastrectomy group(TLG group,n=140,treated with TLG)and laparoscopically assisted gastrectomy group[laparoscopy assisted gastrectomy(LAG)group,n=156,treated with LAG]according to whether or not to perform intra-abdominal gastrointestinal reconstruction.The clinical data of the two groups before,during and after operation were compared.Result:The operation time,postoperative hospitalization time and incision length of TLG group were significantly shorter than those of LAG group,the ventilation time and the time of feeding fluid were earlier than those of LAG group,the amount of intraoperative bleeding was less than that of LAG group,the pain scores after 1 d and 3 d of operation and the level of white blood cells after 1 d of operation were lower than those of LAG group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in the incidence of complications,tumor diameter,proximal and distal margin distance,tumor differentiation,number of lymph node dissection and TNM stage between TLG group and LAG group(P>0.05).Conclusion:Compared with laparoscopic assisted gastrectomy for gastric cancer,total laparoscopic gastrectomy for gastric cancer has less trauma,faster postoperative recovery,shorter postoperative hospital stay,better treatment effect and does not increase the risk of postoperative complications.
作者
许亚龙
刘流
何义仁
刘少军
胡磊
万晓
朱志强
XU Yalong;LIU Liu;HE Yiren;LIU Shaojun;HU Lei;WAN Xiao;ZHU Zhiqiang(Graduate School of Wannan Medical College,Wuhu 241000,China;不详)
出处
《中外医学研究》
2023年第7期1-5,共5页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
安徽省自然科学基金项目(2208085MH201)。
