摘要
目的以长沙市中医医院收治的孕晚期妊娠高血压患者为例,分析血小板参数、凝血功能检验的临床意义.方法选取长沙市中医医院2020年6月-2022年1月收治的92例妊娠期高血压患者为研究组,另选取同时期的健康晚期妊娠者60例为妊晚组,健康孕龄非孕妇女72例为对照组,比较三组血小板平均体积(MPV)、血小板计数(PLT)、血小板分布宽度(PDW)、血小板压积(PCT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、血浆凝血酶原时间(PT)、凝血酶时间(TT)、抗凝血酶-Ⅲ(AT-Ⅲ).结果研究组MPV、FIB高于对照组,而PLT、PDW、PCT、APTT、PT、AT-Ⅲ水平低于对照组(P<0.05);妊晚组PLT、PDW、PCT、APTT、PT、AT-Ⅲ水平低于对照组,FIB高于对照组(P<0.05);研究组MPV、FIB高于妊晚组,PDW、PCT、PT水平低于妊晚组(P<0.05);三组MPV、PLT、PDW、PCT、APTT、FIB、PT、AT-Ⅲ比较,差异明显(P<0.05),而TT水平比较则无差异意义(P>0.05).结论通过动态监测患者血小板参数、凝血功能指标,可及时发现患者血栓前状态,且该指标水平变化与妊娠期高血压疾病发生的关系密切,有助于患者病情诊断及治疗,有效提高患者妊娠安全性,值得推广.
Objective To analyze the clinical significance of platelet parameters and coagulation function tests in patients with pregnancy induced hypertension in the third trimester of pregnancy admitted to our hospital.Methods 92 patients with pregnancy induced hypertension admitted to our hospital from June 2020 to January 2022 were selected as the study group,60 healthy late pregnancy patients in the same period were selected as the late pregnancy group,and 72 healthy non pregnant women of pregnancy age were selected as the control group.The mean platelet volume(MPV),platelet count(PLT),platelet distribution width(PDW),platelet hematocrit(PCT),activated partial thromboplastin time(APTT),fibrinogen(FIB)Plasma prothrombin time(PT),thrombin time(TT)and antithrombin-Ⅲ(AT-Ⅲ).Results The levels of MPV and FIB in the study group were higher than those in the control group,but the levels of PLT,PDW,PCT,APTT,PT and AT-Ⅲ were lower than those in the control group(P<0.05);the levels of PLT,PDW,PCT,APTT,PT and AT-Ⅲ in the late pregnancy group were lower than those in the control group and FIB was higher than those in the control group(P<0.05);the levels of MPV and FIB in the study group were higher than those in the late pregnancy group,and the levels of PDW,PCT and PT were lower than those in the late pregnancy group(P<0.05);the levels of MPV,PLT,PDW,PCT,APTT,FIB,PT and AT-Ⅲ in the three groups were significantly different(P<O.05),but the levels of TT were not significantly different(P>0.05).Conclusion The prethrombotic state of patients can be found in time through dynamic monitoring of platelet parameters and coagulation function indicators,and the level change of these indicators is closely related to the occurrence of hypertensive disorder complicating pregnancy,which is helpful to the diagnosis and treatment of patients'conditions,ffectively improves the safety of patients'pregnancy,and is worthy of promotion.
作者
蹇小乐
Jian Xiaole(Changsha hospital of traditional Chinese medicine,Changsha,Hunan 410001,China)
出处
《首都食品与医药》
2023年第3期95-97,共3页
Capital Food Medicine
关键词
妊娠期高血压
血小板参数
凝血功能指标
临床意义
pregnancy induced hypertension
Platelet parameters
Coagulation function index
Clinical significance
