摘要
目的:探讨右美托咪定对小儿困难气道麻醉期生命体征及苏醒期躁动的影响。方法:选择阳江市阳东区人民医院麻醉科2019年10月-2021年10月收治的困难气道患儿66例,将患儿随机分为常规组与联合组,每组33例。对照组采用七氟烷进行麻醉诱导,联合组在对照组基础上联合右美托咪定进行麻醉诱导。比较两组患儿麻醉诱导前(T_(0))、给药后(T_(1))、插管时(T_(2))、插管后5 min(T_(3))生命体征[心率(HR)、呼吸频率(RR)]、血流动力学[平均动脉压(MAP)、血氧饱和度(SpO_(2))];比较两组患儿苏醒即刻(T_(a))、离开复苏室时(T_(b))、术后1 h(T_(c))行为学评分(FLACC)、Ramsay镇静评分及术后不良反应发生情况。结果:联合组HR在T_(1)、T_(2)、T_(3)时均低于常规组,MAP在T_(2)、T_(3)时均高于常规组,FLACC评分在T_(a)、T_(b)时均低于常规组,Ramsay镇静评分在T_(a)、T_(b)时均高于常规组,不良反应发生率低于常规组(P<0.05)。结论:右美托咪定用于小儿困难气道麻醉诱导中,患儿生命体征、血流动力学稳定,具有良好术后镇痛、镇静效果,术后不良反应发生率低。
Objective:To investigate the effect of Dexmedetomidine on the vital signs during anesthesia and restlessness during recovery in children with difficult airway.Method:Sixty-six children with difficult airway admitted to the Department of Anesthesiology,People’s Hospital of Yangdong District,Yangjiang City from October2019 to October 2021 were selected,they were divided into routine group and combination group by random number table method,33 cases in each group.In the routine group,Sevoflurane was used for induction of anesthesia,the combination group was combined with Dexmedetomidine for induction of anesthesia on the basis of the routine group.The vital signs[heart rate(HR),respiratory rate(RR)]and hemodynamics[mean arterial pressure(MAP),oxygen saturation(SpO_(2))]were compared between the two groups before anesthesia induction(T_(0)),after administration(T_(1)),at intubation(T_(2))and 5 min after intubation(T_(3));behavioral scores(FLACC)and Ramsay sedation scores immediately after recovery(T_(a)),after leaving resuscitation room(T_(b)),1 h after surgery(T_(c))and occurrence of postoperative adverse reactions were compared between the two groups.Result:HR of combination group were lower than those of routine group at T_(1),T_(2)and T_(3),MAP were higher than those of routine group at T_(2)and T_(3),FLACC scores were lower than those of routine group at T_(a)and T_(b),Ramsay sedation scores were higher than those of routine group at T_(a)and T_(b),and the incidence of adverse reactions was lower than that of routine group(P<0.05).Conclusion:When Dexmedetomidine is used for anesthesia induction in children with difficult airway,the vital signs and hemodynamics of children are stable,with good postoperative analgesia and sedation effects,and the incidence of postoperative adverse reactions is low.
作者
周辉
蔡宜良
陈家趁
ZHOU Hui;CAI Yiliang;CHEN Jiachen(People's Hospital of Yangdong District,Yangjiang City,Guangdong Province,Yangjiang 529500,China;不详)
出处
《中国医学创新》
CAS
2023年第6期103-106,共4页
Medical Innovation of China
基金
阳江市医疗卫生类科技计划项目(SF2021133)。
关键词
小儿困难气道
右美托咪定
七氟烷
气管插管
血流动力学
Difficult airway in children
Dexmedetomidine
Sevoflurane
Tracheal intubation
Hemodynamics
