摘要
目的探讨补肾调心治法用于排卵障碍性不孕的价值。方法选择108例排卵障碍性不孕患者,以随机数表法分为观察组与对照组,各54例。对照组予补肾调周中药内服,观察组在对照组用药基础上加用调心中药治法,比较治疗后2组排卵率与妊娠情况、综合疗效,比较2组治疗前后最大排卵日雌二醇(E_(2))及黄体中期孕酮(P)、E_(2)、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、生活质量量表(SF-36)总评分,治疗后随访1年,比较2组抱婴率。结果治疗后,观察组排卵率、妊娠率、抱婴率均显著高于对照组(P<0.05)。2组治疗后最大排卵日E_(2)、黄体中期P均显著高于本组治疗前,观察组治疗后黄体中期E_(2)显著高于本组治疗前(P<0.05);观察组治疗后最大排卵日E_(2)、黄体中期P、黄体中期E_(2)与对照组治疗后比较均显著提高(P<0.05)。治疗后2组HAMD、HAMA总评分均显著低于本组治疗前,SF-36总评分均显著高于本组治疗前(P<0.05);治疗后观察组HAMD、HAMA总评分显著低于对照组,SF-36总评分显著高于对照组(P<0.05)。观察组临床疗效总有效率(90.74%,49/54)显著高于对照组(68.52%,37/54)(P<0.05)。结论在补肾调周法基础上联合调心治法治疗排卵障碍性不孕症,可有效提高临床疗效,能明显改善患者卵泡质量与心理状态,提高患者生活质量,值得临床推广。
Objective To explore the value of the kidney tonifying and mental activity regulating therapy in the treatment of anovulatory infertility.Methods A total of 108 patients were randomly divided into an observation group(n=54)and a control group(n=54).The control group was treated with traditional Chinese medicine for invigorating the kidney and regulating menstruations,while the observation group was treated with traditional Chinese medicine for regulating mental activities on that basis.After treatment,the ovulation rate,pregnancy and TCM syndrome curative effect of the two groups were compared.The total scores of estradiol(E_(2))on the maximum ovulation day,mid luteal progesterone(P),E_(2),Hamilton Depression Scale(HAMD),Hamilton Anxiety Scale(HAMA)and Quality of Life Scale(SF-36)were compared between the two groups before and after treatment.The patients were followed up for one year after treatment,and the baby-holding rates of the two groups were counted and compared.Results The ovulation rate,pregnancy rate and baby holding rate in the observation group were significantly higher than those in the control group after treatment(P<0.05).The maximum ovulation day E_(2)and mid luteal phase P of the two groups after treatment were significantly higher than those before treatment,and the mid luteal phase E_(2)of the observation group after treatment was significantly higher than that before treatment(P<0.05).The maximum ovulation day E_(2),mid luteal P and mid luteal E_(2)in the observation group were significantly higher than those in the control group after treatment(P<0.05).After treatment,the total scores of HAMD and HAMA in the two groups were significantly lower than those before treatment,while the total score of SF-36 was significantly higher than that before treatment(P<0.05).After treatment,the total scores of HAMD and HAMA in the observation group were significantly lower than those in the control group,while the total score of SF-36 was significantly higher than that in the control group(P<0.05).The tota
作者
甘瑾
王进进
高娟
夏亚芳
华彩凤
季佳文
GAN Jin;WANG Jinjin;GAO Juan;XIAYafang;HUA Caifeng;JI Jiawen(Department of Gynecology and Obstetrics,Jiangyin Hospital of Traditional Chinese Medicine,Jiangyin 214400,China)
出处
《长春中医药大学学报》
2023年第3期301-305,共5页
Journal of Changchun University of Chinese Medicine
基金
江苏省中医药科技发展计划项目(YB2020045)。
关键词
中医
补肾调周
调心治法
排卵障碍性不孕
调心安神钩藤汤
Chinese medicine
invigorating kidney for regulating menstruation
mental activity regulating therapy
anovulatory infertility
Tiaoxin Anshen Gouteng Decoction
