摘要
具有抗血栓治疗指征的颅内出血患者在临床实践中并不少见,然而出血后是否启动抗凝或抗血小板治疗以及治疗的时机仍存在争议,缺乏相关指南的推荐意见,此类疾病的治疗决策对临床医师构成了巨大挑战。本文通过检索相关文献,重点分析了不同病因的颅内出血后启动抗凝或抗血小板治疗的血栓栓塞及出血复发的风险,同时呈现目前临床实践中启动抗血栓治疗的时间及方案,为临床医师提供参考。
Patients with intracranial hemorrhage and indications of antithrombotic therapy are common in clinical practice.However,whether and when to start anticoagulant or antiplatelet therapy after intracranial hemorrhage are still debatable.Clinicians are posed with huge challenges without available guidelines.Through reviewing relevant literature,this article analyzed the risks of thromboembolism and hemorrhage recurrence after initiation of anticoagulant or antiplatelet therapy in patients with intracranial hemorrhage due to various etiologies.This article also presented the initiation time and specific antithrombotic plan in current clinical practice,aiming to propose references for clinicians.
作者
李胜德
倪俊
彭斌
Li Shengde;Ni Jun;Peng Bin(Department of Neurology,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2023年第2期204-211,共8页
Chinese Journal of Neurology
基金
国家重点研发计划(2016YFC0901004)。
关键词
颅内出血
抗凝药
血小板聚集抑制剂
血栓栓塞
复发
Intracranial hemorrhage
Anticoagulants
Platelet aggregation inhibitors
Thromboembolism
Recurrence