摘要
目的分析不同冠状动脉损伤程度川崎病(KD)患儿发病早期(确诊后1 d)超声心动图、左心室心肌做功参数。方法选取2021年6—12月在陕西省人民医院确诊的KD患儿50例。根据患儿冠状动脉损伤情况,将其分为研究组1(冠状动脉内径正常、管壁增厚毛糙,20例)、研究组2(冠状动脉扩张,20例)、研究组3(冠状动脉瘤形成,10例)。患儿于确诊后1 d、健康儿童于体检当天进行二维超声心动图检查及二维斑点追踪超声心动图(2D-STE)检查,记录超声心动图参数〔包括左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左心室射血分数(LVEF)及左心室短轴缩短率(LVFS)〕、左心室心肌做功参数〔整体做功指数(GWI)、整体有用功(GCW)、整体无用功(GWW)、整体做功效率(GWE)、整体纵向应变(GLS)〕。结果四组LVEDD、LVESD、LVEF、LVFS比较,差异无统计学意义(P>0.05)。四组GWI、GWW、GWE、GLS比较,差异无统计学意义(P>0.05);研究组3 GCW低于对照组(P<0.05)。结论冠状动脉内径正常、管壁增厚毛糙的KD患儿和伴有冠状动脉扩张的KD患儿发病早期超声心动图、左心室心肌做功参数无异常,伴有冠状动脉瘤形成的KD患儿发病早期超声心动图参数无异常,而其左心室心肌做功参数中的GCW降低。
Objective To analyze the echocardiography and left ventricular myocardial work parameters in Kawasaki disease(KD)children with different degrees of coronary artery injury at the early stage of the disease(1 day after diagnosis).Methods A total of 50 children with KD diagnosed in Shaanxi Provincial People's Hospital from June to December 2021 were selected.According to the condition of coronary artery injury,they were divided into study group 1(20 children with normal coronary artery diameter and rough tube wall thickening),study group 2(20 children with coronary artery expansion)and study group 3(10 children with coronary aneurysm formation).One day after the diagnosis of the children and on the day of physical examination of healthy children,two-dimensional echocardiography and 2D speckle tracking echocardiography(2D-STE)were performed.Echocardiographic parameters[including left ventricular end diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD),left ventricular ejection fraction(LVEF)and left ventricular fraction shortening(LVFS)]and left ventricular myocardial work parameters[global work index(GWI),global constructive work(GCW),global wasted work(GWW),global work efficiency(GWE)and global longitudinal strain(GLS)]were recorded.Results There was no significant difference in LVEDD,LVESD,LVEF and LVFS among the four groups(P>0.05).There was no significant difference in GWI,GWW,GWE and GLS among the four groups(P>0.05);GCW in study group 3 was lower than that in control group(P<0.05).Conclusion The echocardiogram and left ventricular myocardial work parameters of KD children with normal coronary artery diameter and rough tube wall thickening and KD children with coronary artery dilatation at the early stage of disease are not abnormal,the echocardiogram parameters of KD children with coronary aneurysm formation at the early stage of disease are not abnormal,while GCW of left ventricular myocardial work parameters decreases.
作者
娄萍
张雪梅
张丹
赵颖
赵欣
王俊香
金晶
曹玲
LOU Ping;ZHANG Xuemei;ZHANG Dan;ZHAO Ying;ZHAO Xin;WANG Junxiang;JIN Jing;CAO Ling(Ultrasonic Diagnostic Center,Shaanxi Provincial People's Hospital,Xi'an 710068,China)
出处
《实用心脑肺血管病杂志》
2023年第3期113-116,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
陕西省重点研发计划项目(2021KW-66)。
