摘要
肺炎支原体是常见的导致学龄期儿童及青壮年群体发生肺炎的呼吸道病原体。它不仅可以引起呼吸系统疾病,也可以导致多个系统(如血液系统、消化系统、神经系统等)出现相关临床症状。近年来,国内外越来越多的文献指出肺炎支原体可引起机体凝血状态的变化,从而导致多种血栓性疾病,例如肺栓塞,但具体致病机制目前仍不明确。本文将对肺炎支原体引起机体凝血状态改变可能的机制进行综述,旨在为今后临床工作中早期识别及治疗肺炎支原体所致高凝状态提供参考依据。
Mycoplasma pneumoniae is a common respiratory pathogen that causes pneumonia in school-age children and young adults.It can cause not only respiratory diseases,but also related clinical symptoms in multiple systems(such as the blood system,digestive system,nervous system,etc.).In recent years,more and more literatures at home and abroad have indicated that Mycoplasma pneumoniae can cause changes in the coagulation state of the body,thus leading to a variety of thrombotic diseases,such as pulmonary embolism,but the specific pathogenic mechanism is still unclear.In this paper,the possible mechanism of Mycoplasma pneumoniae induced changes in coagulation state of the body will be reviewed in order to provide reference for the early recognition and treatment of hypercoagulation state caused by Mycoplasma pneumoniae in future clinical work.
作者
徐露丹
马莲美
XU Ludan;MA Lianmei(Department of Pediatrics,Affiliated Hospital of Binzhou Medical College,Binzhou Shandong 256600)
关键词
肺炎支原体肺炎
致病机制
高凝状态
血栓形成
Mycoplasma pneumoniae pneumonia
Pathogenic mechanism
High coagulation state
thrombosis