摘要
中国是结核病及结核分枝杆菌潜伏感染高负担国家。结核分枝杆菌潜伏感染及活动性结核病的治疗管理和预后完全不同,现有潜伏感染诊断技术并不能有效预测和鉴别活动性结核病的进展和发生。因此,需要探索更加准确的生物标志物。本文主要就结核分枝杆菌潜伏感染和活动性结核病鉴别诊断生物标志物研究进展及问题进行总结和归纳,并展望其发展方向。
China is a country with a high burden of tuberculosis and latent tuberculosis infection.The treatment and prognosis of latent tuberculosis infection and active tuberculosis are completely different.The current available diagnostic tools for tuberculosis infection cannot effectively predict the progress of infection and differentiate it from active tuberculosis,therefore,more accurate biomarkers need to be developed.The research progress,challenges and prospects of biomarkers for differential diagnosis between latent tuberculosis infection and active tuberculosis were reviewed in the present study.
作者
夏辉
王瑞白
赵雁林
Xia Hui;Wang Ruibai;Zhao Yanlin(National Tuberculosis Reference Laboratory,National Center for Tuberculosis Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;Tuberculosis Department,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)
出处
《中国防痨杂志》
CAS
CSCD
2023年第3期253-259,共7页
Chinese Journal of Antituberculosis
关键词
分枝杆菌
结核
感染
生物学标记
诊断
鉴别
总结性报告(主题)
Mycobacterium tuberculosis
Infection
Biological markers
Diagnosis,differential
Consensus development conferences as topic
