摘要
早产儿由于免疫系统发育不成熟,自身抵抗力和免疫力弱,因而易发生院内感染。且在新生儿重症监护病房(NICU)中,早产儿经验性、预防性抗生素的使用情况较为普遍,过早使用抗生素易引起早产儿肠道菌群失调、肠道致病菌增加,还易引起消化系统疾病,并与早产儿败血症、过敏及神经精神性的疾病发生密切相关。因此,本文从抗生素使用对早产儿肠道菌群的影响进行综述。
Neonatal infants have a high incidence of nosocomial infection due to their immature immune system,weak resistance and immunity.Experimental and preventive antibiotics are commonly used in neonatal intensive care units(NICU).Early use of antibiotics is likely to cause intestinal flora imbalance and increase of intestinal pathogenic bacteria in premature infants.It is also easy to cause digestive system diseases and is closely related to sepsis,allergy and neuropsychiatric diseases in premature infants.Therefore,this article reviews the effects of antibiotic use on intestinal flora in premature infants.
作者
周瑞
张雪芬
张宁
何瑞臻
丁晓华
ZHOU Rui;ZHANG Xue-fen;ZHANG Ning;HE Rui-zhen;DING Xiao-hua(Department of Nursing,School of Nursing,Gansu University of Chinese Medicine,Lanzhou 730000,Gansu,China;Department of Nursing,Gansu Province Maternal and Child Health Hospital,Lanzhou 730050,Gansu,China)
出处
《医学信息》
2023年第3期177-180,共4页
Journal of Medical Information
基金
甘肃省卫生健康行业科研计划项目(编号:GSWSHL2021-009)。
关键词
抗生素
早产儿
肠道菌群
Antibiotics
Premature infants
Intestinal flora
