摘要
目的 对苏州市新型冠状病毒奥密克戎病毒株感染患者,经治疗出院后复检阳性情况进行分析,为出院患者的隔离管理、健康监测及疫情防控提供决策依据。方法 回顾性分析2022年3月13日—2022年5月10日苏州市第五人民医院收治的新型冠状病毒奥密克戎变异株感染患者临床资料,根据出院健康监测期间核酸检测情况分为复阳组及未复阳组,比较分析两组患者的基本信息、疫苗接种情况、首次达到出院标准时间、发病初期淋巴细胞计数等临床特征,并分析复阳组复阳时间、二次入院后达到出院标准时间。结果 637例出院病例中复阳病例88例,复阳率13.8%。复阳组平均年龄明显大于未复阳组(P<0.05),但在性别、体重指数(BMI)及合并基础性疾病上无统计学差异。复阳组发病初期淋巴细胞下降人数比例明显高于非复阳组,有统计学差异(P<0.05)。637例患者疫苗接种针次达2针及以上人数共500例,占比78.5%,两组患者疫苗接种情况无统计学差异。两组患者发病至初次达到出院标准时间间隔中位数均为9天,复阳时间为出院后第1~23天,中位天数为第3天,发生在出院后14天内的占97.7%,复阳后二次达到出院标准时间为3~14天,间隔中位数为3天。结论 高龄、淋巴细胞数作为与复阳相关的独立危险因素值得被重视。较其它病毒株,奥密克戎感染患者核酸转阴及住院时长明显缩短。按新版诊疗方案可以让部分患者提前出院、节约医疗资源,并未对复阳率造成较大影响,新版诊疗指南更科学、合理,能更科学而有效的指导各地疫情防控。
Objective To analyze the positive retest of patients infected with the novel coronavirus Omicron virus strain in Suzhou after treatment and discharge, and to provide a basis for decision-making of isolation management, health monitoring, and epidemic prevention.Methods Retrospective analysis was performed on patients infected with the Ormicrone variant of novel coronavirus admitted to Suzhou Fifth People?s Hospital from March 13, 2022, to May 10, 2022. According to the nucleic acid detection during discharge health monitoring, patients were divided into the re-positive group and the non-re-positive group.Clinical characteristics such as basic information, vaccination status, first time to reach the standard of discharge, and lymphocyte count at the beginning of the disease were compared and analyzed between the two groups.The time of rehabilitation and the standard time of discharge after secondary admission were analyzed.Results Among the 637 discharged patients, 88 cases recovered positive symptoms, with a recovery rate of 13.8%. The mean age of the re-positive group was significantly higher than that of the negative group(P<0.05), but there was no significant difference in sex, body mass index(BMI), or underlying diseases. Compared to the negative group, the number of lymphocytes in the re-positive group decrease dramatically and there was a statistical difference between the data of the two groups(P<0.05). In the re-positive group, more than 500 patients received 2 or more doses of vaccine, but there was no significant statistical difference between two groups.In both groups,the median time interval from onset to first meeting the discharge standard was 9 days;the time for rehabilitation was 1~23 days after discharge,and the median number of days was 3 days;97.7%of the patients occurred within 14 days after discharge;the time for second meeting the discharge standard after rehabilitation was 3~14 days,and the median interval was 3 days.Conclusion Old age and the number of lymphocytes are independent risk fact
作者
张金荣
闵翼
张建平
冯彦军
包紫薇
吴洵洵
刘义安
ZHANG Jin-rong;MIN Yi;ZHANG Jian-ping;FENG Yan-jun;BAO Zi-wei;WU Xun-xun;LIU Yi-an(The Fifth People’s Hospital of Suzhou,Suzhou,Jiangsu 215000,China;Yixing Chinese Medicine Hospital,Wuxi,Jiangsu 214000,China)
出处
《临床肺科杂志》
2023年第3期340-344,共5页
Journal of Clinical Pulmonary Medicine
基金
江苏省中医药管理局新型冠状病毒肺炎中医药防治应急研究专项(No.JSZYJ202201)。
