摘要
去甲乌药碱(higenamine,HG)具有多种生物活性,广泛存在于药用植物中,具有较高的医用价值。由于HG具有β2受体激动作用,近年世界反兴奋剂机构(World Anti-doping Agency,WADA)将其列为禁用物质。目前,含HG中药及其检测方法研究缺乏系统的归纳总结。本文对中药中运动员禁用兴奋剂HG的检测方法进行系统分析,旨在为中药中HG的检测及误用风险防控提供参考,为含兴奋剂中药科学监管提供新思路。
Higenamine(HG)is a bioactive substance,which widely exists in medicinal plants,has high medical values.However,HG is banned by the World Anti-doping Agency(WADA)because of theβ2agonistic activity.At present,the research on traditional Chinese medicine(TCM)containing HG and related detection methods has not been systematically summarized.This paper summarized the detection methods of HG,doping in sport in TCM,hoping to provide a reference for the detection and misuse risk control of HG in TCM,and provide a new idea about the scientific supervision of TCM containing doping.
作者
邬伟魁
严倩茹
宋伟
WU Weikui;YAN Qianru;SONG Wei(Meizhou Institute for Food and Drug Control,Meizhou 514000,China;Department of Pharmacy,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《中国现代应用药学》
CAS
CSCD
北大核心
2023年第1期133-138,共6页
Chinese Journal of Modern Applied Pharmacy
基金
广东省药品监督管理局科技创新项目(2021TDB09)。
关键词
中药
去甲乌药碱
检测
兴奋剂
Β2激动剂
阳性检测结果
traditional Chinese medicine
higenamine
testing
doping
β2 agonists
adverse analytical finding
