摘要
目的探讨基于多模态CT诊断任务对一站式胰腺灌注扫描时相优化方案的可行性。方法收集2018年7月~2020年11月于德阳市人民医院采用第3代双源CT正常胰腺灌注病例72例行回顾性分析,根据不同扫描参数设置分为A组和B组。A组(常规灌注组,24例):密集采集时间1.5 s,24次动态容积扫描,总采集时间94.5 s;B组(时间优化组,48例):密集采集时间2.5 s,19次动态容积扫描,总采集时间75 s。依据灌注数据集重建三种模态CT诊断数据,以评价诊断要求满足情况:基于常规增强图像评价主动脉、胰腺及门静脉对应期像信噪比(SNR)、对比噪声比(CNR);基于常规血管图评价胰周血管变异程度;对比胰腺钩突、胰头、胰体及胰尾灌注参数值,包括血流量(BF)、血容量(BV)、平均通过时间(MTT)及表面通透性(PS)。记录有效辐射剂量。结果两组重建主动脉、胰腺及门静脉对应最佳融合期像SNR、CNR差异均无统计学意义(P>0.05)。8例胃左动脉起源于腹腔干(A组3/24、B组5/48),2例肝右动脉起源于肠系膜上动脉(A组1/24、B组1/48),3例肝左动脉起源于腹腔干(B组3/48),两组中所有图像质量均能支持变异评估。两组各部位正常胰腺灌注参数差异无统计学意义(P>0.05)。2.5 s密集采集方式运用于A组可使平均有效辐射剂量减少约22.8%。结论与1.5 s密集采集方式相比,采用2.5 s密集采集方式的一站式上腹部检查不影响胰腺、血管成像以及灌注分析,并且能降低辐射剂量。
Objective To discuss the optimization of one-stop pancreatic CT perfusion scanning time based on multiple diagnostic tasks.Methods A retrospective analysis was conducted on 72 cases of normal pancreatic perfusion using the third generation dual source CT in Deyang People's Hospital from July 2018 to November 2020.They were divided into group A and group B according to different scanning parameter settings.Group A(routine perfusion group,24 cases):intensive collection time was 1.5 s,24 dynamic volume scans,total collection time was 94.5 s.Group B(time optimization group,48 cases):intensive collection time 2.5 s,19 dynamic volume scans,total collection time 75 s.Three modes of CT diagnostic data were reconstructed according to perfusion data set to evaluate the satisfaction of diagnostic requirements.Signal to noise ratio(SNR)and contrast to noise ratio(CNR)of corresponding phase images of aorta,pancreas and portal vein were evaluated based on conventional enhanced images.Evaluate the degree of peripancreatic vascular variation based on routine angiogram.The perfusion parameters of pancreatic uncinate process,head,body and tail were compared,including blood flow(BF),blood volume(BV),mean transit time(MTT)and surface permeability(PS).Record the effective radiation dose.Results The difference in objective indexes of multi-phase images between A and B group did not had statistical significance(P>0.05).Left gastric artery directly started with celiac axis in 8 cases(A group 3/24,B group 5/48),right hepatic artery directly started with superior mesenterie artery in 2cases(A group 1/24,B group 1/48),left hepatic artery directly started with celiac axis in 3 cases(B group 3/48).All image quality could satisfy the assessment of vascular variations.The difference in perfusion data between A and B group did not achieve statistical significance(P>0.05).With 2.5 sintensive sampling intervalin group A,ED could be reduced by approximately 22.8%.Conclusion Compared with the 1.5 sintensive sampling interval,using 2.5 sintensive sa
作者
孙青
俞溪
明兵
彭金成
邹庆
张仕勇
兰茜琳
刘婷
SUN Qing;YU Xi;MING Bing;PENG Jincheng;ZOU Qing;ZHANG Shiyong;LAN Xilin;LIU Ting(School of Medical Imaging,North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Radiology,Deyang People's Hospital,Deyang 618000,Sichuan,China)
出处
《西部医学》
2023年第2期287-292,共6页
Medical Journal of West China
基金
四川省医学科研课题(S17031)
四川省卫生和计划生育委员会科研课题(18PJ136)。
