摘要
目的:分析孕晚期正常胎儿及轻中度单纯性侧脑室扩张胎儿脑发育的弥散加权成像(DWI),探讨表观扩散系数(ADC)在轻中度单纯性侧脑室扩张诊断中的价值。方法:选取74例单纯性侧脑室扩张胎儿为观察组,同期31例孕晚期正常胎儿为正常组;观察组再根据病情分为轻度组(n=57)和中度组(n=17)。胎儿均行DWI检查,比较各组胎儿不同脑区ADC值,分析其与孕周的关系及对单纯性侧脑室扩张诊断的价值。结果:正常组胎儿左侧及右侧额叶、顶叶、颞叶、枕叶白质、基底节、丘脑、小脑半球ADC值比较,差异无统计学意义(P>0.05);基底节、丘脑及小脑ADC值低于其他脑区(P<0.05)。观察组胎儿左侧及右侧各脑区ADC值比较,差异无统计学意义(P>0.05)。观察组与正常组胎儿各脑区平均ADC值比较,差异无统计学意义(P>0.05)。相关性分析显示,顶叶、枕叶及颞叶ADC值与孕周呈负相关(r=-0.534、-0.419、-0.476,P<0.05)。结论:孕晚期正常胎儿不同脑区的ADC值不同,正常组胎儿顶叶、枕叶及颞叶ADC值随孕周增加而减低,单纯性轻中度侧脑室扩张胎儿各脑区ADC值与正常胎儿无明显差异,有助于评估孕晚期胎儿脑发育情况。
Objective:To analyze the diffusion weighted imaging(DWI) of brain development in normal fetuses and fetuses with mild and moderate isolated ventriculomegaly in late pregnancy, and to explore the value of apparent diffusion coefficient(ADC) in the diagnosis of mild and moderate isolated ventriculomegaly.Methods:74 fetuses with isolated ventriculomegaly were selected as the observation group, while 31 fetuses with normal late pregnancy were selected as the normal group.The observation group was divided into mild group(n=57) and moderate group(n=17) according to the condition.All fetuses were examined by DWI.ADC values of different brain regions in each group were compared, and their relationship with gestational age and diagnostic value for isolated ventriculo megaly were analyzed.Results:There was no significant difference in ADC values between the left and right frontal lobes, parietal lobes, temporal lobes, occipital lobes, basal ganglia, thalamus, and cerebellar hemispheres of the fetus in the normal group(P>0.05).The ADC values in basal ganglia, thalamus and cerebellum in normal fetus were lower than those in other brain regions(P<0.05).There was no significant difference in ADC values between the left and right brain regions in the observation group(P>0.05).There was no significant difference in the average ADC values of fetal brain regions between the observation group and the normal group(P>0.05).Correlation analysis showed that the ADC values in parietal lobe, occipital lobe and temporal lobe were negatively correlated with gestational weeks(r=-0.534,-0.419,-0.476,P<0.05).Conclusion:ADC values in different brain regions of normal fetuses in late pregnancy are different, the ADC values in parietal lobe, occipital lobe and temporal lobe decreased with the increasing of gestational age, and no significant difference of ADC values in every brain region is found among fetuses with mild and moderate isolated ventriculomegaly and normal fetuses.These results are helpful to assess the fetal brain development inlat
作者
程金梅
潘健
郭媛媛
周海鹰
CHENG Jin-mei;PAN Jian;GUO Yuan-yuan;ZHOU Hai-ying(Department of Radiology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of General Practice,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China;Department of Obstetrics and Gynaecology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China)
出处
《川北医学院学报》
CAS
2023年第1期80-83,95,共5页
Journal of North Sichuan Medical College
基金
四川省南充市市校科技战略合作项目(20SXQT0039)。
关键词
弥散加权成像
表观扩散系数
胎儿
脑发育
单纯性侧脑室扩张
Diffusion weighted imaging
Apparent diffusion coefficient
Fetus
Brain development
Isolated ventriculomegaly
