摘要
目的探索非小细胞肺癌患者术后早期发热的预测因素及其对术后早期发热的影响。方法回顾性分析2020年7月1日至2020年12月31日于中国医科大学肿瘤医院行手术治疗的254例非小细胞肺癌患者的临床病理资料。根据患者术后7 d内体温是否≥38.0℃,分为发热组(n=55)及非发热组(n=199),并比较各因素对于术后早期发热发生的影响。结果发热组中有吸烟史的患者比例较高(P=0.030)。发热组术后第1天首次体温及其与基础体温的差值、术后第1天最高体温及其与基础体温的差值和术后第1天平均体温及其与基础体温的差值均高于未发热组(均P<0.05)。发热组术后第1天白细胞数目、手术前后白细胞数目差值及手术前后中性粒细胞数目差值均高于未发热组(均P<0.05)。与非发热组比较,发热组行肺叶切除术患者占比更高、手术时间更长、术中出血量更大且术后住院时间更长(均P<0.05)。两组在住院费用方面比较,差异无统计学意义(P=0.602)。结论吸烟史、肺叶切除术、手术时间、术中出血量、白细胞数目及其变化和中性粒细胞数目及其变化是肺癌术后早期发热的相关预测因子。
Objective To explore the predictive factors of early postoperative fever in patients with non-small-cell lung cancer and its influence on early postoperative fever.Methods The clinicopathological data of 254 patients with non-small-cell lung cancer who underwent surgery in Cancer Hospital of China Medical University from July 1st,2020 to December 31st,2020 were retrospectively analyzed.The patients were divided into the fever group(n=55)and non-fever group(n=199)according to whether the body temperature was≥38.0℃within 7 days after operation.The influence of each factor on the occurrence of early fever after operation was compared.Results The proportion of patients with smoking history was higher in the fever group(P=0.030).The first body temperature on the first postoperative day and its difference with basal body temperature,the highest body temperature on the first postoperative day and its difference with basal body temperature,and the average body temperature on the first postoperative day and its difference with basal body temperature in the fever group were all higher than those in the non-fever group(all P<0.05).The white blood cell count on the first postoperative day,the difference of white blood cell count before and after operation,and the difference of neutrophil count before and after operation in the fever group were all significantly higher than those in the non-fever group(all P<0.05).Compared with the non-fever group,the proportion of patients undergoing lobectomy in the fever group was higher,the operative time was longer,the intraoperative blood loss was greater,and the postoperative hospital stay was longer(all P<0.05).There was no significant difference in hospitalization expense between the two groups(P=0.602).Conclusions Smoking history,lobectomy,operative time,intraoperative blood loss,white blood cell count,neutrophil count and the changes of white blood cell count and neutrophil count are related predictors of early postoperative fever.
作者
金娜
姜婷婷
邹晓影
Jin Na;Jiang Tingting;Zou Xiaoying(Department of Thoracic Surgery,Cancer Hospital of China Medical University,Shenyang 110042,China)
出处
《实用肿瘤杂志》
CAS
2023年第1期54-58,共5页
Journal of Practical Oncology
关键词
非小细胞肺癌
术后早期发热
体温
non-small-cell lung cancer
early postoperative fever
body temperature
