摘要
目的分析补肾健骨汤辅助治疗老年胸腰椎压缩性骨折的效果。方法50例老年胸腰椎压缩性骨折患者,采用随机数字表法分为对照组和观察组,每组25例。所有患者均进行经皮椎体成形术(PVP)治疗,对照组患者给予阿仑膦酸钠肠溶片及碳酸钙D3片治疗,观察组在对照组基础上增加补肾健骨汤辅助治疗。比较两组疼痛缓解时间、住院时间、治疗效果、再次骨折发生率及血液流变学指标、骨密度、骨碱性磷酸酶、髋关节功能评分。结果观察组疼痛缓解时间、住院时间分别为(3.45±0.26)、(7.21±0.13)d,均短于对照组的(5.78±1.25)、(9.21±1.34)d,差异有统计学意义(P<0.05)。治疗前,两组骨密度、骨碱性磷酸酶、髋关节功能评分及红细胞聚集指数、全血比粘度、血浆比粘度比较,差异无统计学意义(P>0.05);治疗后,两组骨密度、骨碱性磷酸酶、髋关节功能评分及红细胞聚集指数、全血比粘度、血浆比粘度均优于本组治疗前,且观察组骨密度(0.93±0.05)g/cm^(2)、骨碱性磷酸酶(85.52±2.26)U/L、髋关节功能评分(93.55±4.25)分及红细胞聚集指数(9.21±0.21)、全血比粘度(4.11±0.21)mPa·s、血浆比粘度(1.34±0.23)均优于对照组的(0.82±0.04)g/cm^(2)、(96.21±1.12)U/L、(81.33±2.45)分、(10.21±0.41)、(5.32±0.21)mPa·s、(1.67±0.12)mPa·s,差异有统计学意义(P<0.05)。观察组总有效率100.00%高于对照组的76.00%,差异有统计学意义(P<0.05)。观察组再次骨折发生率4.00%(1/25)低于对照组的28.00%(7/25),差异有统计学意义(P<0.05)。结论补肾健骨汤辅助治疗老年胸腰椎压缩性骨折患者的预后良好,可改善血液流变学指标、骨密度、骨碱性磷酸酶水平和腰椎功能,缓解疼痛,降低再次骨折发生率低,临床可积极推广应用。
Objective To analyze the effect of Bushen Jiangu Decoction on treatment of thoracolumbar vertebral compression fracture in the elderly.Methods A total of 50 elderly patients with thoracolumbar vertebral compression fracture were divided into a control group and an observation group according to the random numerical table,with 25 cases in each group.All patients were treated with percutaneous vertebroplasty(PVP).Patients in the control group were treated with alendronate sodium enteric-coated tablets and calcium carbonate D3 tablets,while the observation group was treated with the addition of Bushen Jiangu Decoction on the basis of the control group.Both groups were compared in terms of pain relief time,hospital stay,therapeutic effect,incidence of re-fracture and blood rheology index,bone density,bone alkaline phosphatase and hip function score.Results The pain relief time and hospital stay in the observation group were(3.45±0.26)and(7.21±0.13)d,which were shorter than(5.78±1.25)and(9.21±1.34)d in the control group,and the differences were statistically significant(P<0.05).Before treatment,there were no statistically significant differences between the two groups in terms of bone density,bone alkaline phosphatase,hip function score,erythrocyte aggregation index,and plasma specific viscosity(P>0.05).After treatment,the bone density,bone alkaline phosphatase,hip function score and erythrocyte aggregation index,whole blood specific viscosity,and plasma specific viscosity in both groups were better than those before treatment in this group;the observation group had bone density of(0.93±0.05)g/cm^(2),bone alkaline phosphatase of(85.52±2.26)U/L,hip function score of(93.55±4.25)points and erythrocyte aggregation index of(9.21±0.21),whole blood specific viscosity of(4.11±0.21)mPa·s,and plasma specific viscosity of(1.34±0.23)mPa·s,which were better than(0.82±0.04)g/cm2,(96.21±1.12)U/L,(81.33±2.45)points,(10.21±0.41),(5.32±0.21)mPa·s,(1.67±0.12)mPa·s of the control group;the differences were statistical
作者
何振国
HE Zhen-guo(Traditional Chinese Medicine Hospital of Dongzhou District,Fushun 113006,China)
出处
《中国实用医药》
2023年第2期154-157,共4页
China Practical Medicine
关键词
补肾健骨汤
老年胸腰椎压缩性骨折
髋关节功能
Bushen Jiangu Decoction
Thoracolumbar vertebral compression fracture in the elderly
Hip joint function
