摘要
The controllable construction of light-emitting organometallic supramolecular materials integrating stimulus responses and biological applications is still a major challenge today.In this work,emissive organometallic assemblies based on AgI/AuI and mesoionic carbene-decorated tetraphenylethene(MIC-TPE)ligands have been synthesized and characterized.Photophysical studies showed that these organometallic assemblies[M_(4)(2)_(2)](OTf)_(4) not only fluoresce in various dilute solutions,resulting from the rigidification of MIC-TPE ligands upon complexation,but also show tunable fluorescence wavelengths and intensity behaviors in mixed solvent systems and at varying temperatures while in solution,and mechanical pressure stimulus-responsive fluorescent features in the solid state.Furthermore,the organometallic cages[M_(4)(2)_(2)](OTf)_(4)(M=Ag and Au)were successfully employed for cell imaging and showed the potential of anticancer activity,making them promising candidates for cancer theranostics.This work provides a simple and efficient method to prepare highly emissive and stimulus-responsive organometallic materials and paves the way for related biological applications such as cancer cell imaging and targeted therapy.
基金
The authors gratefully acknowledge financial support from the National Natural Science Foundation(NSFC)(grant nos.22025107,21722105,and 21771146)
the National Youth Top-notch Talent Support Program of China,the Key Science and Technology Innovation Team of Shaanxi Province(nos.2019TD-007 and 2019JLZ-02)
the FM&EM International Joint Laboratory of Northwest University.
