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乙酰化脱氧雪腐镰刀菌烯醇污染、毒性及转化研究进展

Progress in Research on Contamination,Toxicity and Transformation of Acetylated Deoxynivalenol
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摘要 脱氧雪腐镰刀菌烯醇(deoxynivalenol,DON)俗称呕吐毒素,是禾谷镰刀菌等真菌产生的次级代谢产物,是谷物原料及其制品中最常见的污染物之一。DON的产生往往伴随其主要乙酰化衍生物3-乙酰基-DON和15-乙酰基-DON的产生,这些衍生物表现出与DON相似甚至更强的毒性,因而增加了谷物及其制品的食用安全风险。本文简述了DON乙酰化衍生物的产生、检测技术及污染现状,重点分析了DON乙酰化衍生物的毒性及转化研究进展,以期为粮食中DON乙酰化衍生物的降解和防控研究提供理论参考。 Deoxynivalenol(DON,commonly known as vomitoxin)is one of the most common pollutants in grains and grain products,and it is a secondary metabolite produced by fungi such as Fusarium graminearum.DON is usually produced concurrently with its acetylated derivatives,including 3-acetyl-DON and 15-acetyl-DON,which show similar or even higher toxicity than DON,increasing the safety risk of grains and grain products.In this paper,we briefly describe the current status of research on the production,detection technologies and pollution status of DON acetylated derivatives.We also review recent progress in research on the toxicity and transformation of DON acetylated derivatives.Through this review,we hope to provide a theoretical foundation for future research on the degradation,prevention and control of DON acetylated derivatives in foods.
作者 王瑞虎 李萌萌 关二旗 刘远晓 金瑞 卞科 赵世通 WANG Ruihu;LI Mengmeng;GUAN Erqi;LIU Yuanxiao;JIN Rui;BIAN Ke;ZHAO Shitong(College of Food Science and Engineering,Henan University of Technology,Zhengzhou 450001,China)
出处 《食品科学》 EI CAS CSCD 北大核心 2023年第1期345-352,共8页 Food Science
基金 “十三五”国家重点研发计划战略性国际科技创新合作重点专项(2018YFE0206000) 国家自然科学基金青年科学基金项目(31801654) 2020年度河南工业大学青年骨干教师培育计划项目。
关键词 乙酰化脱氧雪腐镰刀菌烯醇 污染 毒性 转化 防控 acetylated deoxynivalenol contamination,toxicity transformation prevention
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