摘要
急性呼吸窘迫综合征(ARDS)是危重病及呼吸衰竭患者病死率高的常见原因。ARDS时死腔分数(VD/VT)增大与肺损伤加重及死亡独立相关。VD/VT可通过床旁测量动脉血气和呼气末二氧化碳容易获得。床旁早期重视和应用VD/VT这个指标,有助于更好理解ARDS的病理生理特征,指导临床治疗,并能更好地评估病情严重程度及临床预后。
Acute respiratory distress syndrome(ARDS)is a common cause of critical illness and high mortality from respiratory failure.Increased dead space fraction(VD/VT)was independently associated with lung injury and mortality of ARDS.VD/VT is readily obtained by bedside measurements of arterial blood gas and end-tidal carbon dioxide.Early attention and application of VD/VT as an indicator will help to better understand the pathophysiological of ARDS,guide clinical treatment,and better assess the severity and clinical prognosis of the disease.
作者
马四清
王志健
郭利涛
Ma Siqing;Wang Zhijian;Guo Litao(Department of Critical Care Medicine,Qinghai Provincial People's Hospital,Xining 810007,Qinghai,China;Department of Critical Care Medicine,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,Shanxi,China)
出处
《中华危重病急救医学》
CAS
CSCD
北大核心
2022年第12期1333-1336,共4页
Chinese Critical Care Medicine
基金
青海省高原重症医学重点实验室(2020-81)
高原低氧损害防治重症医学创新创业团队(2020-66)
青海省重点研发与转化计划项目(2019-SF-132)。
关键词
死腔分数
急性呼吸窘迫综合征
机械通气
新型冠状病毒肺炎
预后
Dead space fraction
Acute respiratory syndrome
Mechanical ventilation
Coronavirus disease 2019
Prognosis
