摘要
目的 分析青年缺血性脑卒中患者的临床特征。方法 回顾性分析青年缺血性脑卒中患者100例(青年组,年龄18~45岁)和中老年缺血性脑卒中患者100例(中老年组,年龄>45岁)病例资料。比较两组临床资料、实验室指标、脑卒中评定和TOAST分型。结果 青年组男性、吸烟史和高尿酸血症比例高于中老年组(P<0.05或P<0.01)。青年组抗凝血酶Ⅲ、SCr、尿酸和TG水平高于中老年组(P<0.05或P<0.01)。入院和出院时青年组美国国立卫生研究院卒中量表评分均低于中老年组(P<0.05)。两组大动脉粥样硬化型比例相仿(47%vs.49%)(P>0.05),但青年组不明原因型比例高于中老年组(16%vs.3%)(P<0.05)。结论 青年缺血性脑卒中患者吸烟和高尿酸血症比例高,病情严重程度低,TOAST分型以大动脉粥样硬化型为主,但不明原因型比例高。
Objective To analyze the clinical features of young patients with ischemic stroke.MethodsThe data of 100 young patients with ischemic stroke(group A,aged 18-45 years old)and 100 middle-aged and elderly patients with ischemic stroke(group B,age>45 years old)were retrospectively analyzed.The clinical data,laboratory indicators,stroke assessment and TOAST classification of two groups were compared.ResultsThe proportions of male,smoking history and hyperuricemia in group A were higher than those in group B(P<0.05 or P<0.01).Serum levels of antithrombin II,SCr,uric acid and TG in group A were higher than those in group B(P<o.05 or P<0.01).The scores of National Institutes of Health Stroke Scale at admission and discharge in group A were lower than those in group B(P<0.05).The proportion of the patients with atherosclerotic type of large arteries in groups of A and B was similar(47%vs.49%)(P>0.05),while the proportion of unexplained type in group A was higher than that in group B(16%vs.3%)(P<0.05).ConclusionYoung patients with ischemic stroke have higher proportion of smoking and hyperuricemia,but lower severity of disease,in whom atherosclerosis of large arteries is predominant,but the proportion of unexplained type is higher in their TOAST classification.
作者
张少君
王琴
颜艳
ZHANG Shaojun;WANG Qin;YAN Yan(Clinical College of Neurology,Neurosurgery and Neurorehabilitation,Tianjin Medical University,Tianjin300000,CHINA)
出处
《江苏医药》
CAS
2022年第12期1196-1199,共4页
Jiangsu Medical Journal
基金
国家自然科学基金(81972349)。
