摘要
目的:分析青年缺血性卒中病人的临床特点,指导青年缺血性卒中的防治。方法:选取2014-2017年神经内科住院的75例青年缺血性卒中病人作为青年卒中组,选取同期住院的80例中老年缺血性卒中病人作为中老年卒中组,进行危险因素、中国缺血性卒中(CISS)分型、脑动脉狭窄分布和预后评价的分析。结果:2组性别分布差异无统计学意义(P>0.05)。中老年卒中组高血压、糖尿病、高脂血症、既往短暂性脑缺血发作病史率高于青年组,而吸烟、酗酒、高同型半胱氨酸血症率低于青年组(P<0.05~P<0.01);青年卒中组在CISS分型上以大动脉粥样硬化型为主(53.33%),2组CISS亚型分布差异具有统计学意义(P<0.05)。青年卒中组前循环狭窄率高于中老年组,而后循环狭窄低于中老年组(P<0.05)。青年卒中组预后效果明显优于中老年卒中组,2组预后评分差异具有统计学意义(P<0.01)。结论:吸烟、酗酒、高同型半胱氨酸血症已经成为青年缺血性卒中的常见危险因素;在CISS分型中,大动脉粥样硬化型常见分型;狭窄部位以前循环狭窄为主;同时短期预后优于中老年卒中病人。
Objective:To analyze the clinical characristics of ischemic stroke in young patients,and provide the guidance in prevention and treatment of disease.Methods:Seventy-five young patients with ischemic stroke and 80 middle-aged and old patients with ischemic stroke were divided into the young group and middle-aged and old group,respectively.The risk factors,Chinese ischemic stroke subclassification(CISS)typing,cerebral artery stenosis and prognosis in two groups were evaluated.Results:The difference of gender distribution between two groups was not statistically significant(P>0.05).The incidence rates of hypertension,diabetes mellitus,hyperlipidaemia,TIA disease history in middle-aged and old group were higher than those in young group,and the incidence rates of smoking,alcoholism and hyperhomocysteinemia in middle-aged old group were lower than those in young group(P<0.05 to P<0.01).The large-artery atherosclerosis in young group was the main type of CISS classification(53.3%),and the difference of CISS subtype between two groups was statistically significant(P<0.05).The anterior circulation stenosis rate in young group was higher than that in middle-aged and old group,but the posterior circulation stenosis rate in young group was lower than that in middle-aged and old group(P<0.05).The prognosis in young group was significantly better than that in middle-aged and old group(P<0.05).The difference of the prognosis score between two groups was statiscally siginificant(P<0.01).Conclusions:Smoking,alcoholism and hyperhomocysteinemia are the most common risk factors in young patients with ischemic stroke.LAA is the most common subtype of CISS.The anterior circulation stenosis is more.The short-term prognosis in young patients with ischemic stroke is better than that in middle-aged and old patients with ischemic stroke.
作者
姜伟韬
袁良津
胡艳兵
施雪英
JIANG Wei-tao;YUAN Liang-jin;HU Yan-bing;SHI Xue-ying(Department of Neurology,Anqing Municipal Hospital,Anqing Anhui 246003,China)
出处
《蚌埠医学院学报》
CAS
2019年第8期1045-1047,共3页
Journal of Bengbu Medical College
关键词
缺血性卒中
青年
危险因素
ischemic stroke
young people
risk factor
