摘要
胃肠道间质瘤(GIST)是起源于消化系统间叶组织的肿瘤。在临床中胃肠道间质瘤的治疗主要以手术治疗及术后的靶向药物治疗为主。随着医学的不断发展以及研究的深入,已经发现一些影响GIST预后的相关因素,目前已知因素有肿瘤原发部位、大小、核分裂数、核抗原Ki-67(antigen Ki-67)、肿瘤是否破裂等。本文查阅大量文献,将根据以上相关影响因素做一个综述。
Gastrointestinal stromal tumor(GIST)is a tumor originating in the mesenchymal tissue of the digestive system.In clinic,the treatment of gastrointestinal stromal tumor is mainly surgical treatment and postoperative targeted drug therapy.With the continuous development of medicine and more in-depth studies,some factors related to the prognosis of GIST have been found.At present,known factors include the primary site,size,mitotic number,proliferation cell nuclear antigen(Ki-67)index,and whether the tumor rupture.In this paper,a large number of relevant literature will be consulted,according to the above related factors to do a review.
作者
赵娜
崔云甫
Zhao Na;Cui Yunfu(First Department of General Surgery,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086,China)
出处
《中华实验外科杂志》
CAS
北大核心
2022年第12期2502-2505,共4页
Chinese Journal of Experimental Surgery
关键词
胃肠道间质瘤
生物学行为
外科手术
分子靶向治疗
预后
Gastrointestinal stromal tumor
Biological behavior
Surgery
Molecular targeted therapy
Prognosis
